| Motif | HIF1A.H12CORE.0.P.B |
| Gene (human) | HIF1A (GeneCards) |
| Gene synonyms (human) | BHLHE78, MOP1, PASD8 |
| Gene (mouse) | Hif1a |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HIF1A.H12CORE.0.P.B |
| Gene (human) | HIF1A (GeneCards) |
| Gene synonyms (human) | BHLHE78, MOP1, PASD8 |
| Gene (mouse) | Hif1a |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 11 |
| Consensus | bbvKACGTGMh |
| GC content | 58.84% |
| Information content (bits; total / per base) | 10.592 / 0.963 |
| Data sources | ChIP-Seq |
| Aligned words | 218 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 24 (137) | 0.847 | 0.935 | 0.781 | 0.899 | 0.808 | 0.925 | 2.9 | 4.014 | 178.347 | 450.444 |
| Mouse | 4 (25) | 0.85 | 0.888 | 0.75 | 0.798 | 0.831 | 0.884 | 2.803 | 3.314 | 196.022 | 313.585 |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 18.972 | 11.551 | 0.279 | 0.173 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | PAS {1.2.5} (TFClass) |
| TF subfamily | PAS-AHR {1.2.5.1} (TFClass) |
| TFClass ID | TFClass: 1.2.5.1.5 |
| HGNC | HGNC:4910 |
| MGI | MGI:106918 |
| EntrezGene (human) | GeneID:3091 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15251 (SSTAR profile) |
| UniProt ID (human) | HIF1A_HUMAN |
| UniProt ID (mouse) | HIF1A_MOUSE |
| UniProt AC (human) | Q16665 (TFClass) |
| UniProt AC (mouse) | Q61221 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 24 human, 4 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | HIF1A.H12CORE.0.P.B.pcm |
| PWM | HIF1A.H12CORE.0.P.B.pwm |
| PFM | HIF1A.H12CORE.0.P.B.pfm |
| Alignment | HIF1A.H12CORE.0.P.B.words.tsv |
| Threshold to P-value map | HIF1A.H12CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | HIF1A.H12CORE.0.P.B_jaspar_format.txt |
| MEME format | HIF1A.H12CORE.0.P.B_meme_format.meme |
| Transfac format | HIF1A.H12CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 24.0 | 30.0 | 107.0 | 57.0 |
| 02 | 40.0 | 45.0 | 89.0 | 44.0 |
| 03 | 54.0 | 51.0 | 102.0 | 11.0 |
| 04 | 35.0 | 9.0 | 55.0 | 119.0 |
| 05 | 189.0 | 5.0 | 19.0 | 5.0 |
| 06 | 0.0 | 212.0 | 1.0 | 5.0 |
| 07 | 3.0 | 0.0 | 214.0 | 1.0 |
| 08 | 0.0 | 0.0 | 0.0 | 218.0 |
| 09 | 0.0 | 0.0 | 218.0 | 0.0 |
| 10 | 82.0 | 103.0 | 10.0 | 23.0 |
| 11 | 43.0 | 112.0 | 29.0 | 34.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.11 | 0.138 | 0.491 | 0.261 |
| 02 | 0.183 | 0.206 | 0.408 | 0.202 |
| 03 | 0.248 | 0.234 | 0.468 | 0.05 |
| 04 | 0.161 | 0.041 | 0.252 | 0.546 |
| 05 | 0.867 | 0.023 | 0.087 | 0.023 |
| 06 | 0.0 | 0.972 | 0.005 | 0.023 |
| 07 | 0.014 | 0.0 | 0.982 | 0.005 |
| 08 | 0.0 | 0.0 | 0.0 | 1.0 |
| 09 | 0.0 | 0.0 | 1.0 | 0.0 |
| 10 | 0.376 | 0.472 | 0.046 | 0.106 |
| 11 | 0.197 | 0.514 | 0.133 | 0.156 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.79 | -0.578 | 0.663 | 0.044 |
| 02 | -0.301 | -0.186 | 0.481 | -0.208 |
| 03 | -0.009 | -0.065 | 0.615 | -1.509 |
| 04 | -0.43 | -1.686 | 0.009 | 0.768 |
| 05 | 1.226 | -2.175 | -1.01 | -2.175 |
| 06 | -3.725 | 1.34 | -3.17 | -2.175 |
| 07 | -2.553 | -3.725 | 1.35 | -3.17 |
| 08 | -3.725 | -3.725 | -3.725 | 1.368 |
| 09 | -3.725 | -3.725 | 1.368 | -3.725 |
| 10 | 0.4 | 0.625 | -1.594 | -0.83 |
| 11 | -0.231 | 0.708 | -0.61 | -0.457 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.71862 |
| 0.0005 | 5.71494 |
| 0.0001 | 7.56948 |