HIC1.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HIC1.H12INVIVO.0.PSM.A
Gene (human)	HIC1 (GeneCards)
Gene synonyms (human)	ZBTB29
Gene (mouse)	Hic1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	hbvTGCCMnS
GC content	63.51%
Information content (bits; total / per base)	7.031 / 0.703
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	262

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (20)	0.744	0.776	0.568	0.595	0.676	0.701	1.656	1.829	69.593	111.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.873	0.843	0.818	0.798	0.776	0.763
Overall, 4 experiments	best	0.982	0.972	0.973	0.956	0.962	0.941
Methyl HT-SELEX, 1 experiments	median	0.982	0.972	0.971	0.954	0.956	0.934
Methyl HT-SELEX, 1 experiments	best	0.982	0.972	0.971	0.954	0.956	0.934
Non-Methyl HT-SELEX, 3 experiments	median	0.766	0.718	0.665	0.641	0.597	0.592
Non-Methyl HT-SELEX, 3 experiments	best	0.98	0.968	0.973	0.956	0.962	0.941

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	HIC {2.3.4.17} (TFClass)
TFClass ID	TFClass: 2.3.4.17.1
HGNC	HGNC:4909
MGI	MGI:1338010
EntrezGene (human)	GeneID:3090 (SSTAR profile)
EntrezGene (mouse)	GeneID:15248 (SSTAR profile)
UniProt ID (human)	HIC1_HUMAN
UniProt ID (mouse)	HIC1_MOUSE
UniProt AC (human)	Q14526 (TFClass)
UniProt AC (mouse)	Q9R1Y5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	HIC1.H12INVIVO.0.PSM.A.pcm
PWM	HIC1.H12INVIVO.0.PSM.A.pwm
PFM	HIC1.H12INVIVO.0.PSM.A.pfm
Alignment	HIC1.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	HIC1.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	HIC1.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	HIC1.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	HIC1.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	HIC1.H12INVIVO.0.PSM.A_homer_format_0.001.txt HIC1.H12INVIVO.0.PSM.A_homer_format_0.0005.txt HIC1.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	50.0	118.0	38.0	56.0
02	33.0	58.0	82.0	89.0
03	40.0	85.0	128.0	9.0
04	5.0	5.0	1.0	251.0
05	9.0	3.0	242.0	8.0
06	39.0	217.0	3.0	3.0
07	24.0	211.0	3.0	24.0
08	100.0	132.0	18.0	12.0
09	81.0	49.0	62.0	70.0
10	13.0	151.0	58.0	40.0

PFM

	A	C	G	T
01	0.191	0.45	0.145	0.214
02	0.126	0.221	0.313	0.34
03	0.153	0.324	0.489	0.034
04	0.019	0.019	0.004	0.958
05	0.034	0.011	0.924	0.031
06	0.149	0.828	0.011	0.011
07	0.092	0.805	0.011	0.092
08	0.382	0.504	0.069	0.046
09	0.309	0.187	0.237	0.267
10	0.05	0.576	0.221	0.153

PWM

	A	C	G	T
01	-0.264	0.579	-0.53	-0.153
02	-0.665	-0.119	0.22	0.301
03	-0.48	0.256	0.66	-1.862
04	-2.348	-2.348	-3.331	1.328
05	-1.862	-2.723	1.292	-1.963
06	-0.504	1.183	-2.723	-2.723
07	-0.969	1.155	-2.723	-0.969
08	0.416	0.69	-1.238	-1.608
09	0.208	-0.283	-0.054	0.065
10	-1.536	0.823	-0.119	-0.48

Standard thresholds

P-value	Threshold
0.001	5.15505
0.0005	5.759265
0.0001	6.854295