MotifHIC1.H12INVITRO.0.PSM.A
Gene (human)HIC1
(GeneCards)
Gene synonyms (human)ZBTB29
Gene (mouse)Hic1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length10
ConsensusndTGCCMhhn
GC content58.63%
Information content (bits; total / per base)9.313 / 0.931
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words6768

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.727 0.745 0.512 0.591 0.601 0.613 1.264 1.451 63.416 101.377

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.903 0.884 0.841 0.83 0.794 0.789
best 0.995 0.992 0.99 0.985 0.982 0.973
Methyl HT-SELEX, 1 experiments median 0.994 0.991 0.988 0.981 0.976 0.965
best 0.994 0.991 0.988 0.981 0.976 0.965
Non-Methyl HT-SELEX, 3 experiments median 0.812 0.777 0.695 0.678 0.612 0.613
best 0.995 0.992 0.99 0.985 0.982 0.973
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMultiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamilyHIC {2.3.4.17} (TFClass)
TFClass IDTFClass: 2.3.4.17.1
HGNCHGNC:4909
MGIMGI:1338010
EntrezGene (human)GeneID:3090
(SSTAR profile)
EntrezGene (mouse)GeneID:15248
(SSTAR profile)
UniProt ID (human)HIC1_HUMAN
UniProt ID (mouse)HIC1_MOUSE
UniProt AC (human)Q14526
(TFClass)
UniProt AC (mouse)Q9R1Y5
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011932.251603.251650.251582.25
023131.0503.02479.0655.0
035.023.00.06740.0
04155.00.06613.00.0
050.06768.00.00.0
060.06768.00.00.0
073655.02896.060.0157.0
082572.01641.0871.01684.0
091035.03285.0857.01591.0
101339.752347.751315.751764.75
PFM
ACGT
010.2850.2370.2440.234
020.4630.0740.3660.097
030.0010.0030.00.996
040.0230.00.9770.0
050.01.00.00.0
060.01.00.00.0
070.540.4280.0090.023
080.380.2420.1290.249
090.1530.4850.1270.235
100.1980.3470.1940.261
PWM
ACGT
010.133-0.054-0.025-0.067
020.615-1.210.382-0.947
03-5.46-4.208-6.6441.381
04-2.377-6.6441.362-6.644
05-6.6441.385-6.644-6.644
06-6.6441.385-6.644-6.644
070.7690.537-3.305-2.365
080.418-0.031-0.663-0.005
09-0.4910.663-0.679-0.061
10-0.2330.327-0.2510.042
Standard thresholds
P-value Threshold
0.001 5.63018
0.0005 6.38061
0.0001 7.41395