HIC1.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HIC1.H12CORE.0.PSM.A
Gene (human)	HIC1 (GeneCards)
Gene synonyms (human)	ZBTB29
Gene (mouse)	Hic1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	ndTGCCMhhn
GC content	58.63%
Information content (bits; total / per base)	9.313 / 0.931
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	6768

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (20)	0.727	0.745	0.512	0.591	0.601	0.613	1.264	1.451	63.416	101.377

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.903	0.884	0.841	0.83	0.794	0.789
Overall, 4 experiments	best	0.995	0.992	0.99	0.985	0.982	0.973
Methyl HT-SELEX, 1 experiments	median	0.994	0.991	0.988	0.981	0.976	0.965
Methyl HT-SELEX, 1 experiments	best	0.994	0.991	0.988	0.981	0.976	0.965
Non-Methyl HT-SELEX, 3 experiments	median	0.812	0.777	0.695	0.678	0.612	0.613
Non-Methyl HT-SELEX, 3 experiments	best	0.995	0.992	0.99	0.985	0.982	0.973

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	HIC {2.3.4.17} (TFClass)
TFClass ID	TFClass: 2.3.4.17.1
HGNC	HGNC:4909
MGI	MGI:1338010
EntrezGene (human)	GeneID:3090 (SSTAR profile)
EntrezGene (mouse)	GeneID:15248 (SSTAR profile)
UniProt ID (human)	HIC1_HUMAN
UniProt ID (mouse)	HIC1_MOUSE
UniProt AC (human)	Q14526 (TFClass)
UniProt AC (mouse)	Q9R1Y5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	HIC1.H12CORE.0.PSM.A.pcm
PWM	HIC1.H12CORE.0.PSM.A.pwm
PFM	HIC1.H12CORE.0.PSM.A.pfm
Alignment	HIC1.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	HIC1.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	HIC1.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	HIC1.H12CORE.0.PSM.A_meme_format.meme
Transfac format	HIC1.H12CORE.0.PSM.A_transfac_format.txt
Homer format	HIC1.H12CORE.0.PSM.A_homer_format_0.001.txt HIC1.H12CORE.0.PSM.A_homer_format_0.0005.txt HIC1.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1932.25	1603.25	1650.25	1582.25
02	3131.0	503.0	2479.0	655.0
03	5.0	23.0	0.0	6740.0
04	155.0	0.0	6613.0	0.0
05	0.0	6768.0	0.0	0.0
06	0.0	6768.0	0.0	0.0
07	3655.0	2896.0	60.0	157.0
08	2572.0	1641.0	871.0	1684.0
09	1035.0	3285.0	857.0	1591.0
10	1339.75	2347.75	1315.75	1764.75

PFM

	A	C	G	T
01	0.285	0.237	0.244	0.234
02	0.463	0.074	0.366	0.097
03	0.001	0.003	0.0	0.996
04	0.023	0.0	0.977	0.0
05	0.0	1.0	0.0	0.0
06	0.0	1.0	0.0	0.0
07	0.54	0.428	0.009	0.023
08	0.38	0.242	0.129	0.249
09	0.153	0.485	0.127	0.235
10	0.198	0.347	0.194	0.261

PWM

	A	C	G	T
01	0.133	-0.054	-0.025	-0.067
02	0.615	-1.21	0.382	-0.947
03	-5.46	-4.208	-6.644	1.381
04	-2.377	-6.644	1.362	-6.644
05	-6.644	1.385	-6.644	-6.644
06	-6.644	1.385	-6.644	-6.644
07	0.769	0.537	-3.305	-2.365
08	0.418	-0.031	-0.663	-0.005
09	-0.491	0.663	-0.679	-0.061
10	-0.233	0.327	-0.251	0.042

Standard thresholds

P-value	Threshold
0.001	5.63018
0.0005	6.38061
0.0001	7.41395