MotifHEY2.H12INVITRO.0.S.B
Gene (human)HEY2
(GeneCards)
Gene synonyms (human)BHLHB32, CHF1, GRL, HERP, HERP1, HRT2
Gene (mouse)Hey2
Gene synonyms (mouse)Chf1, Herp, Herp1, Hesr2, Hrt2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnvCACGTKhn
GC content64.59%
Information content (bits; total / per base)9.439 / 0.944
Data sourcesHT-SELEX
Aligned words9473

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 5 experiments median 0.924 0.896 0.821 0.795 0.724 0.71
best 0.995 0.992 0.989 0.983 0.932 0.927

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.83 0.575 0.761 0.573
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyHairy-related {1.2.4} (TFClass)
TF subfamilyHAIRY {1.2.4.1} (TFClass)
TFClass IDTFClass: 1.2.4.1.9
HGNCHGNC:4881
MGIMGI:1341884
EntrezGene (human)GeneID:23493
(SSTAR profile)
EntrezGene (mouse)GeneID:15214
(SSTAR profile)
UniProt ID (human)HEY2_HUMAN
UniProt ID (mouse)HEY2_MOUSE
UniProt AC (human)Q9UBP5
(TFClass)
UniProt AC (mouse)Q9QUS4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 0
PCM
ACGT
012000.252523.252991.251958.25
021319.752709.754442.751000.75
03237.08733.00.0503.0
049390.00.00.083.0
050.09436.00.037.0
060.0476.08980.017.0
070.03901.05.05567.0
08619.0727.06845.01282.0
091781.53270.5481.53939.5
101854.253440.252223.251955.25
PFM
ACGT
010.2110.2660.3160.207
020.1390.2860.4690.106
030.0250.9220.00.053
040.9910.00.00.009
050.00.9960.00.004
060.00.050.9480.002
070.00.4120.0010.588
080.0650.0770.7230.135
090.1880.3450.0510.416
100.1960.3630.2350.206
PWM
ACGT
01-0.1690.0630.233-0.19
02-0.5840.1350.629-0.86
03-2.2931.304-6.943-1.546
041.377-6.943-6.943-3.325
05-6.9431.382-6.943-4.1
06-6.943-1.6011.332-4.811
07-6.9430.499-5.7840.854
08-1.339-1.1791.061-0.613
09-0.2840.323-1.5890.509
10-0.2440.373-0.063-0.191
Standard thresholds
P-value Threshold
0.001 5.1503
0.0005 5.99511
0.0001 7.59842