MotifHEY1.H12INVITRO.0.S.B
Gene (human)HEY1
(GeneCards)
Gene synonyms (human)BHLHB31, CHF2, HERP2, HESR1, HRT1
Gene (mouse)Hey1
Gene synonyms (mouse)Herp2, Hesr1, Hrt1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnnKCACGTGbb
GC content64.99%
Information content (bits; total / per base)12.86 / 1.169
Data sourcesHT-SELEX
Aligned words6127

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.886 0.876 0.779 0.771 0.691 0.69
best 0.965 0.947 0.905 0.879 0.825 0.8

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.982 0.817 0.951 0.577
batch 2 0.653 0.356 0.644 0.429
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyHairy-related {1.2.4} (TFClass)
TF subfamilyHAIRY {1.2.4.1} (TFClass)
TFClass IDTFClass: 1.2.4.1.8
HGNCHGNC:4880
MGIMGI:1341800
EntrezGene (human)GeneID:23462
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)HEY1_HUMAN
UniProt ID (mouse)HEY1_MOUSE
UniProt AC (human)Q9Y5J3
(TFClass)
UniProt AC (mouse)Q9WV93
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
011495.01187.01846.01599.0
02726.25726.253484.251190.25
03366.0441.04872.0448.0
0470.06049.08.00.0
056127.00.00.00.0
060.06126.01.00.0
070.00.06127.00.0
080.0642.00.05485.0
0986.07.06006.028.0
10743.251244.251105.253034.25
111011.02418.01512.01186.0
PFM
ACGT
010.2440.1940.3010.261
020.1190.1190.5690.194
030.060.0720.7950.073
040.0110.9870.0010.0
051.00.00.00.0
060.01.00.00.0
070.00.01.00.0
080.00.1050.00.895
090.0140.0010.980.005
100.1210.2030.180.495
110.1650.3950.2470.194
PWM
ACGT
01-0.024-0.2550.1860.043
02-0.745-0.7450.821-0.252
03-1.427-1.2421.156-1.226
04-3.0561.372-5.015-6.556
051.385-6.556-6.556-6.556
06-6.5561.385-6.179-6.556
07-6.556-6.5561.385-6.556
08-6.556-0.868-6.5561.275
09-2.856-5.1191.365-3.928
10-0.722-0.208-0.3260.683
11-0.4150.456-0.013-0.255
Standard thresholds
P-value Threshold
0.001 2.435595
0.0005 4.199105
0.0001 7.41187