MotifHESX1.H12INVIVO.1.S.D
Gene (human)HESX1
(GeneCards)
Gene synonyms (human)HANF
Gene (mouse)Hesx1
Gene synonyms (mouse)Hes-1, Rpx
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length16
ConsensusdWWWdWYTAATTAnbn
GC content19.49%
Information content (bits; total / per base)15.753 / 0.985
Data sourcesHT-SELEX
Aligned words652

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.751 0.74 0.613 0.626 0.546 0.57
best 0.849 0.853 0.634 0.676 0.554 0.595
Methyl HT-SELEX, 1 experiments median 0.728 0.705 0.612 0.614 0.554 0.567
best 0.728 0.705 0.612 0.614 0.554 0.567
Non-Methyl HT-SELEX, 3 experiments median 0.775 0.769 0.614 0.638 0.541 0.574
best 0.849 0.853 0.634 0.676 0.552 0.595

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.888 0.517 0.798 0.458
batch 2 0.579 0.145 0.478 0.385
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyHESX {3.1.3.10} (TFClass)
TFClass IDTFClass: 3.1.3.10.1
HGNCHGNC:4877
MGIMGI:96071
EntrezGene (human)GeneID:8820
(SSTAR profile)
EntrezGene (mouse)GeneID:15209
(SSTAR profile)
UniProt ID (human)HESX1_HUMAN
UniProt ID (mouse)HESX1_MOUSE
UniProt AC (human)Q9UBX0
(TFClass)
UniProt AC (mouse)Q61658
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01307.7536.7570.75236.75
02408.062.013.0169.0
03219.06.016.0411.0
04178.029.045.0400.0
05340.027.0108.0177.0
06332.07.0138.0175.0
0717.0209.059.0367.0
080.0127.00.0525.0
09652.00.00.00.0
10652.00.00.00.0
110.00.00.0652.0
120.00.00.0652.0
13652.00.00.00.0
14295.062.0233.062.0
1570.75355.7593.75131.75
16157.25183.25152.25159.25
PFM
ACGT
010.4720.0560.1090.363
020.6260.0950.020.259
030.3360.0090.0250.63
040.2730.0440.0690.613
050.5210.0410.1660.271
060.5090.0110.2120.268
070.0260.3210.090.563
080.00.1950.00.805
091.00.00.00.0
101.00.00.00.0
110.00.00.01.0
120.00.00.01.0
131.00.00.00.0
140.4520.0950.3570.095
150.1090.5460.1440.202
160.2410.2810.2340.244
PWM
ACGT
010.631-1.456-0.8220.37
020.912-0.951-2.4210.036
030.293-3.073-2.2350.919
040.087-1.682-1.2620.892
050.73-1.75-0.4070.082
060.706-2.95-0.1650.07
07-2.1790.246-0.9990.806
08-4.621-0.247-4.6211.163
091.379-4.621-4.621-4.621
101.379-4.621-4.621-4.621
11-4.621-4.621-4.6211.379
12-4.621-4.621-4.6211.379
131.379-4.621-4.621-4.621
140.589-0.9510.354-0.951
15-0.8220.775-0.546-0.211
16-0.0360.116-0.068-0.023
Standard thresholds
P-value Threshold
0.001 1.72781
0.0005 3.15661
0.0001 6.18371