Motif | HESX1.H12CORE.1.S.B |
Gene (human) | HESX1 (GeneCards) |
Gene synonyms (human) | HANF |
Gene (mouse) | Hesx1 |
Gene synonyms (mouse) | Hes-1, Rpx |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | HESX1.H12CORE.1.S.B |
Gene (human) | HESX1 (GeneCards) |
Gene synonyms (human) | HANF |
Gene (mouse) | Hesx1 |
Gene synonyms (mouse) | Hes-1, Rpx |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 16 |
Consensus | dWWWdWYTAATTAnbn |
GC content | 19.49% |
Information content (bits; total / per base) | 15.753 / 0.985 |
Data sources | HT-SELEX |
Aligned words | 652 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.751 | 0.74 | 0.613 | 0.626 | 0.546 | 0.57 |
best | 0.849 | 0.853 | 0.634 | 0.676 | 0.554 | 0.595 | |
Methyl HT-SELEX, 1 experiments | median | 0.728 | 0.705 | 0.612 | 0.614 | 0.554 | 0.567 |
best | 0.728 | 0.705 | 0.612 | 0.614 | 0.554 | 0.567 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.775 | 0.769 | 0.614 | 0.638 | 0.541 | 0.574 |
best | 0.849 | 0.853 | 0.634 | 0.676 | 0.552 | 0.595 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.888 | 0.517 | 0.798 | 0.458 |
batch 2 | 0.579 | 0.145 | 0.478 | 0.385 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | HESX {3.1.3.10} (TFClass) |
TFClass ID | TFClass: 3.1.3.10.1 |
HGNC | HGNC:4877 |
MGI | MGI:96071 |
EntrezGene (human) | GeneID:8820 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15209 (SSTAR profile) |
UniProt ID (human) | HESX1_HUMAN |
UniProt ID (mouse) | HESX1_MOUSE |
UniProt AC (human) | Q9UBX0 (TFClass) |
UniProt AC (mouse) | Q61658 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | HESX1.H12CORE.1.S.B.pcm |
PWM | HESX1.H12CORE.1.S.B.pwm |
PFM | HESX1.H12CORE.1.S.B.pfm |
Alignment | HESX1.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | HESX1.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | HESX1.H12CORE.1.S.B_jaspar_format.txt |
MEME format | HESX1.H12CORE.1.S.B_meme_format.meme |
Transfac format | HESX1.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 307.75 | 36.75 | 70.75 | 236.75 |
02 | 408.0 | 62.0 | 13.0 | 169.0 |
03 | 219.0 | 6.0 | 16.0 | 411.0 |
04 | 178.0 | 29.0 | 45.0 | 400.0 |
05 | 340.0 | 27.0 | 108.0 | 177.0 |
06 | 332.0 | 7.0 | 138.0 | 175.0 |
07 | 17.0 | 209.0 | 59.0 | 367.0 |
08 | 0.0 | 127.0 | 0.0 | 525.0 |
09 | 652.0 | 0.0 | 0.0 | 0.0 |
10 | 652.0 | 0.0 | 0.0 | 0.0 |
11 | 0.0 | 0.0 | 0.0 | 652.0 |
12 | 0.0 | 0.0 | 0.0 | 652.0 |
13 | 652.0 | 0.0 | 0.0 | 0.0 |
14 | 295.0 | 62.0 | 233.0 | 62.0 |
15 | 70.75 | 355.75 | 93.75 | 131.75 |
16 | 157.25 | 183.25 | 152.25 | 159.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.472 | 0.056 | 0.109 | 0.363 |
02 | 0.626 | 0.095 | 0.02 | 0.259 |
03 | 0.336 | 0.009 | 0.025 | 0.63 |
04 | 0.273 | 0.044 | 0.069 | 0.613 |
05 | 0.521 | 0.041 | 0.166 | 0.271 |
06 | 0.509 | 0.011 | 0.212 | 0.268 |
07 | 0.026 | 0.321 | 0.09 | 0.563 |
08 | 0.0 | 0.195 | 0.0 | 0.805 |
09 | 1.0 | 0.0 | 0.0 | 0.0 |
10 | 1.0 | 0.0 | 0.0 | 0.0 |
11 | 0.0 | 0.0 | 0.0 | 1.0 |
12 | 0.0 | 0.0 | 0.0 | 1.0 |
13 | 1.0 | 0.0 | 0.0 | 0.0 |
14 | 0.452 | 0.095 | 0.357 | 0.095 |
15 | 0.109 | 0.546 | 0.144 | 0.202 |
16 | 0.241 | 0.281 | 0.234 | 0.244 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.631 | -1.456 | -0.822 | 0.37 |
02 | 0.912 | -0.951 | -2.421 | 0.036 |
03 | 0.293 | -3.073 | -2.235 | 0.919 |
04 | 0.087 | -1.682 | -1.262 | 0.892 |
05 | 0.73 | -1.75 | -0.407 | 0.082 |
06 | 0.706 | -2.95 | -0.165 | 0.07 |
07 | -2.179 | 0.246 | -0.999 | 0.806 |
08 | -4.621 | -0.247 | -4.621 | 1.163 |
09 | 1.379 | -4.621 | -4.621 | -4.621 |
10 | 1.379 | -4.621 | -4.621 | -4.621 |
11 | -4.621 | -4.621 | -4.621 | 1.379 |
12 | -4.621 | -4.621 | -4.621 | 1.379 |
13 | 1.379 | -4.621 | -4.621 | -4.621 |
14 | 0.589 | -0.951 | 0.354 | -0.951 |
15 | -0.822 | 0.775 | -0.546 | -0.211 |
16 | -0.036 | 0.116 | -0.068 | -0.023 |
P-value | Threshold |
---|---|
0.001 | 1.72781 |
0.0005 | 3.15661 |
0.0001 | 6.18371 |