MotifHESX1.H12CORE.0.SM.B
Gene (human)HESX1
(GeneCards)
Gene synonyms (human)HANF
Gene (mouse)Hesx1
Gene synonyms (mouse)Hes-1, Rpx
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusdnbAATTAvbn
GC content25.21%
Information content (bits; total / per base)10.524 / 0.957
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9427

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.762 0.741 0.625 0.632 0.553 0.576
best 0.85 0.84 0.655 0.682 0.567 0.599
Methyl HT-SELEX, 1 experiments median 0.744 0.712 0.63 0.624 0.567 0.575
best 0.744 0.712 0.63 0.624 0.567 0.575
Non-Methyl HT-SELEX, 3 experiments median 0.779 0.769 0.62 0.641 0.545 0.576
best 0.85 0.84 0.655 0.682 0.561 0.599

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.916 0.658 0.853 0.502
batch 2 0.573 0.132 0.542 0.446
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyHESX {3.1.3.10} (TFClass)
TFClass IDTFClass: 3.1.3.10.1
HGNCHGNC:4877
MGIMGI:96071
EntrezGene (human)GeneID:8820
(SSTAR profile)
EntrezGene (mouse)GeneID:15209
(SSTAR profile)
UniProt ID (human)HESX1_HUMAN
UniProt ID (mouse)HESX1_MOUSE
UniProt AC (human)Q9UBX0
(TFClass)
UniProt AC (mouse)Q61658
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
013041.251212.251862.253311.25
021823.752101.751817.753683.75
03773.03339.01000.04315.0
049351.018.057.01.0
059426.01.00.00.0
060.00.00.09427.0
070.00.00.09427.0
089126.00.0301.00.0
093797.01362.02964.01304.0
101586.254314.251597.251929.25
112994.752307.751883.752240.75
PFM
ACGT
010.3230.1290.1980.351
020.1930.2230.1930.391
030.0820.3540.1060.458
040.9920.0020.0060.0
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
080.9680.00.0320.0
090.4030.1440.3140.138
100.1680.4580.1690.205
110.3180.2450.20.238
PWM
ACGT
010.255-0.664-0.2350.34
02-0.256-0.114-0.2590.446
03-1.1130.348-0.8560.604
041.377-4.756-3.684-6.576
051.385-6.576-6.938-6.938
06-6.938-6.938-6.9381.386
07-6.938-6.938-6.9381.386
081.353-6.938-2.051-6.938
090.477-0.5480.229-0.591
10-0.3950.604-0.389-0.2
110.239-0.021-0.224-0.05
Standard thresholds
P-value Threshold
0.001 4.52887
0.0005 6.258185
0.0001 7.72788