Motif | HESX1.H12CORE.0.SM.B |
Gene (human) | HESX1 (GeneCards) |
Gene synonyms (human) | HANF |
Gene (mouse) | Hesx1 |
Gene synonyms (mouse) | Hes-1, Rpx |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | HESX1.H12CORE.0.SM.B |
Gene (human) | HESX1 (GeneCards) |
Gene synonyms (human) | HANF |
Gene (mouse) | Hesx1 |
Gene synonyms (mouse) | Hes-1, Rpx |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 11 |
Consensus | dnbAATTAvbn |
GC content | 25.21% |
Information content (bits; total / per base) | 10.524 / 0.957 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9427 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.762 | 0.741 | 0.625 | 0.632 | 0.553 | 0.576 |
best | 0.85 | 0.84 | 0.655 | 0.682 | 0.567 | 0.599 | |
Methyl HT-SELEX, 1 experiments | median | 0.744 | 0.712 | 0.63 | 0.624 | 0.567 | 0.575 |
best | 0.744 | 0.712 | 0.63 | 0.624 | 0.567 | 0.575 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.779 | 0.769 | 0.62 | 0.641 | 0.545 | 0.576 |
best | 0.85 | 0.84 | 0.655 | 0.682 | 0.561 | 0.599 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.916 | 0.658 | 0.853 | 0.502 |
batch 2 | 0.573 | 0.132 | 0.542 | 0.446 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | HESX {3.1.3.10} (TFClass) |
TFClass ID | TFClass: 3.1.3.10.1 |
HGNC | HGNC:4877 |
MGI | MGI:96071 |
EntrezGene (human) | GeneID:8820 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15209 (SSTAR profile) |
UniProt ID (human) | HESX1_HUMAN |
UniProt ID (mouse) | HESX1_MOUSE |
UniProt AC (human) | Q9UBX0 (TFClass) |
UniProt AC (mouse) | Q61658 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | HESX1.H12CORE.0.SM.B.pcm |
PWM | HESX1.H12CORE.0.SM.B.pwm |
PFM | HESX1.H12CORE.0.SM.B.pfm |
Alignment | HESX1.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | HESX1.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | HESX1.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | HESX1.H12CORE.0.SM.B_meme_format.meme |
Transfac format | HESX1.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3041.25 | 1212.25 | 1862.25 | 3311.25 |
02 | 1823.75 | 2101.75 | 1817.75 | 3683.75 |
03 | 773.0 | 3339.0 | 1000.0 | 4315.0 |
04 | 9351.0 | 18.0 | 57.0 | 1.0 |
05 | 9426.0 | 1.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 9427.0 |
07 | 0.0 | 0.0 | 0.0 | 9427.0 |
08 | 9126.0 | 0.0 | 301.0 | 0.0 |
09 | 3797.0 | 1362.0 | 2964.0 | 1304.0 |
10 | 1586.25 | 4314.25 | 1597.25 | 1929.25 |
11 | 2994.75 | 2307.75 | 1883.75 | 2240.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.323 | 0.129 | 0.198 | 0.351 |
02 | 0.193 | 0.223 | 0.193 | 0.391 |
03 | 0.082 | 0.354 | 0.106 | 0.458 |
04 | 0.992 | 0.002 | 0.006 | 0.0 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 1.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.968 | 0.0 | 0.032 | 0.0 |
09 | 0.403 | 0.144 | 0.314 | 0.138 |
10 | 0.168 | 0.458 | 0.169 | 0.205 |
11 | 0.318 | 0.245 | 0.2 | 0.238 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.255 | -0.664 | -0.235 | 0.34 |
02 | -0.256 | -0.114 | -0.259 | 0.446 |
03 | -1.113 | 0.348 | -0.856 | 0.604 |
04 | 1.377 | -4.756 | -3.684 | -6.576 |
05 | 1.385 | -6.576 | -6.938 | -6.938 |
06 | -6.938 | -6.938 | -6.938 | 1.386 |
07 | -6.938 | -6.938 | -6.938 | 1.386 |
08 | 1.353 | -6.938 | -2.051 | -6.938 |
09 | 0.477 | -0.548 | 0.229 | -0.591 |
10 | -0.395 | 0.604 | -0.389 | -0.2 |
11 | 0.239 | -0.021 | -0.224 | -0.05 |
P-value | Threshold |
---|---|
0.001 | 4.52887 |
0.0005 | 6.258185 |
0.0001 | 7.72788 |