MotifHES5.H12INVIVO.0.SM.D
Gene (human)HES5
(GeneCards)
Gene synonyms (human)BHLHB38
Gene (mouse)Hes5
Gene synonyms (mouse)Hes-5
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length14
ConsensusndhGGCACGTGYYn
GC content64.59%
Information content (bits; total / per base)15.775 / 1.127
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6631

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.809 0.818 0.659 0.676 0.586 0.605
best 1.0 0.999 0.999 0.999 0.997 0.997
Methyl HT-SELEX, 1 experiments median 0.991 0.989 0.927 0.917 0.827 0.818
best 0.991 0.989 0.927 0.917 0.827 0.818
Non-Methyl HT-SELEX, 4 experiments median 0.759 0.774 0.63 0.648 0.571 0.588
best 1.0 0.999 0.999 0.999 0.997 0.997

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.579 0.207 0.364 0.011
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyHairy-related {1.2.4} (TFClass)
TF subfamilyHAIRY {1.2.4.1} (TFClass)
TFClass IDTFClass: 1.2.4.1.5
HGNCHGNC:19764
MGIMGI:104876
EntrezGene (human)GeneID:388585
(SSTAR profile)
EntrezGene (mouse)GeneID:15208
(SSTAR profile)
UniProt ID (human)HES5_HUMAN
UniProt ID (mouse)HES5_MOUSE
UniProt AC (human)Q5TA89
(TFClass)
UniProt AC (mouse)P70120
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
011048.51945.51537.52099.5
022379.0919.01394.01939.0
031372.02187.0847.02225.0
04362.040.06182.047.0
05488.0129.06010.04.0
063.06627.01.00.0
076631.00.00.00.0
081.06617.02.011.0
09122.04.06502.03.0
107.0327.04.06293.0
1127.018.06459.0127.0
1266.02354.0809.03402.0
13362.04465.0865.0939.0
141716.751546.752167.751199.75
PFM
ACGT
010.1580.2930.2320.317
020.3590.1390.210.292
030.2070.330.1280.336
040.0550.0060.9320.007
050.0740.0190.9060.001
060.00.9990.00.0
071.00.00.00.0
080.00.9980.00.002
090.0180.0010.9810.0
100.0010.0490.0010.949
110.0040.0030.9740.019
120.010.3550.1220.513
130.0550.6730.130.142
140.2590.2330.3270.181
PWM
ACGT
01-0.4570.16-0.0750.236
020.361-0.589-0.1730.157
03-0.1890.277-0.670.294
04-1.517-3.6721.315-3.519
05-1.22-2.5381.287-5.59
06-5.7661.385-6.251-6.626
071.385-6.626-6.626-6.626
08-6.2511.383-5.979-4.834
09-2.593-5.591.366-5.766
10-5.195-1.618-5.591.333
11-4.04-4.4091.359-2.553
12-3.1920.35-0.7160.718
13-1.5170.99-0.649-0.567
140.035-0.0690.268-0.323
Standard thresholds
P-value Threshold
0.001 0.76421
0.0005 2.43856
0.0001 5.793365