HES1.H12INVITRO.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HES1.H12INVITRO.0.S.C
Gene (human)	HES1 (GeneCards)
Gene synonyms (human)	BHLHB39, HL, HRY
Gene (mouse)	Hes1
Gene synonyms (mouse)	Hes-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	23
Consensus	nndGSCACGTGbSdbvCRCGbGn
GC content	66.76%
Information content (bits; total / per base)	20.159 / 0.876
Data sources	HT-SELEX
Aligned words	1296

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.997	0.996	0.985	0.981
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.997	0.996	0.985	0.981

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Hairy-related {1.2.4} (TFClass)
TF subfamily	HAIRY {1.2.4.1} (TFClass)
TFClass ID	TFClass: 1.2.4.1.1
HGNC	HGNC:5192
MGI	MGI:104853
EntrezGene (human)	GeneID:3280 (SSTAR profile)
EntrezGene (mouse)	GeneID:15205 (SSTAR profile)
UniProt ID (human)	HES1_HUMAN
UniProt ID (mouse)	HES1_MOUSE
UniProt AC (human)	Q14469 (TFClass)
UniProt AC (mouse)	P35428 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	HES1.H12INVITRO.0.S.C.pcm
PWM	HES1.H12INVITRO.0.S.C.pwm
PFM	HES1.H12INVITRO.0.S.C.pfm
Alignment	HES1.H12INVITRO.0.S.C.words.tsv
Threshold to P-value map	HES1.H12INVITRO.0.S.C.thr
Motif in other formats
JASPAR format	HES1.H12INVITRO.0.S.C_jaspar_format.txt
MEME format	HES1.H12INVITRO.0.S.C_meme_format.meme
Transfac format	HES1.H12INVITRO.0.S.C_transfac_format.txt
Homer format	HES1.H12INVITRO.0.S.C_homer_format_0.001.txt HES1.H12INVITRO.0.S.C_homer_format_0.0005.txt HES1.H12INVITRO.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	319.0	345.0	318.0	314.0
02	456.5	181.5	346.5	311.5
03	406.0	73.0	226.0	591.0
04	61.0	33.0	1148.0	54.0
05	168.0	254.0	846.0	28.0
06	0.0	1296.0	0.0	0.0
07	1221.0	0.0	74.0	1.0
08	0.0	1295.0	1.0	0.0
09	0.0	0.0	1296.0	0.0
10	0.0	263.0	0.0	1033.0
11	0.0	0.0	1287.0	9.0
12	48.0	592.0	311.0	345.0
13	130.0	796.0	228.0	142.0
14	561.0	128.0	161.0	446.0
15	150.0	257.0	708.0	181.0
16	219.0	232.0	738.0	107.0
17	73.0	1076.0	113.0	34.0
18	782.0	115.0	358.0	41.0
19	126.0	1052.0	64.0	54.0
20	68.0	116.0	1087.0	25.0
21	60.0	496.0	139.0	601.0
22	39.75	93.75	1047.75	114.75
23	184.0	350.0	357.0	405.0

PFM

	A	C	G	T
01	0.246	0.266	0.245	0.242
02	0.352	0.14	0.267	0.24
03	0.313	0.056	0.174	0.456
04	0.047	0.025	0.886	0.042
05	0.13	0.196	0.653	0.022
06	0.0	1.0	0.0	0.0
07	0.942	0.0	0.057	0.001
08	0.0	0.999	0.001	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.203	0.0	0.797
11	0.0	0.0	0.993	0.007
12	0.037	0.457	0.24	0.266
13	0.1	0.614	0.176	0.11
14	0.433	0.099	0.124	0.344
15	0.116	0.198	0.546	0.14
16	0.169	0.179	0.569	0.083
17	0.056	0.83	0.087	0.026
18	0.603	0.089	0.276	0.032
19	0.097	0.812	0.049	0.042
20	0.052	0.09	0.839	0.019
21	0.046	0.383	0.107	0.464
22	0.031	0.072	0.808	0.089
23	0.142	0.27	0.275	0.313

PWM

	A	C	G	T
01	-0.015	0.062	-0.019	-0.031
02	0.341	-0.575	0.067	-0.039
03	0.224	-1.472	-0.358	0.599
04	-1.646	-2.237	1.261	-1.765
05	-0.652	-0.242	0.956	-2.392
06	-5.203	1.382	-5.203	-5.203
07	1.323	-5.203	-1.458	-4.76
08	-5.203	1.381	-4.76	-5.203
09	-5.203	-5.203	1.382	-5.203
10	-5.203	-0.207	-5.203	1.156
11	-5.203	-5.203	1.375	-3.407
12	-1.878	0.6	-0.041	0.062
13	-0.905	0.896	-0.349	-0.818
14	0.547	-0.92	-0.694	0.318
15	-0.764	-0.23	0.779	-0.578
16	-0.389	-0.332	0.82	-1.097
17	-1.472	1.196	-1.043	-2.209
18	0.878	-1.026	0.099	-2.03
19	-0.936	1.174	-1.6	-1.765
20	-1.541	-1.017	1.207	-2.498
21	-1.662	0.424	-0.839	0.615
22	-2.06	-1.227	1.17	-1.028
23	-0.562	0.077	0.096	0.222

Standard thresholds

P-value	Threshold
0.001	-0.43029
0.0005	1.16556
0.0001	4.50121