MotifHEN2.H12INVITRO.0.SM.B
Gene (human)NHLH2
(GeneCards)
Gene synonyms (human)BHLHA34, HEN2, KIAA0490
Gene (mouse)Nhlh2
Gene synonyms (mouse)Hen2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusndKGdCGCAGCTGSKn
GC content68.52%
Information content (bits; total / per base)18.531 / 1.158
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9992

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.997 0.996 0.95 0.95 0.853 0.867
best 1.0 1.0 0.999 0.999 0.974 0.975
Methyl HT-SELEX, 1 experiments median 0.995 0.993 0.901 0.901 0.732 0.759
best 0.995 0.993 0.901 0.901 0.732 0.759
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.999 0.999 0.974 0.975
best 1.0 1.0 0.999 0.999 0.974 0.975
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyTAL-HEN {1.2.3.1} (TFClass)
TFClass IDTFClass: 1.2.3.1.5
HGNCHGNC:7818
MGIMGI:97324
EntrezGene (human)GeneID:4808
(SSTAR profile)
EntrezGene (mouse)GeneID:18072
(SSTAR profile)
UniProt ID (human)HEN2_HUMAN
UniProt ID (mouse)HEN2_MOUSE
UniProt AC (human)Q02577
(TFClass)
UniProt AC (mouse)Q64221
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012548.51761.53412.52269.5
022070.25702.255671.251548.25
031026.0342.06858.01766.0
04622.0157.08214.0999.0
055135.0916.02626.01315.0
061327.08517.091.057.0
07182.0137.09372.0301.0
080.09988.01.03.0
099991.00.00.01.0
100.043.09912.037.0
11142.09653.0197.00.0
120.01.00.09991.0
131.00.09987.04.0
141067.06893.01297.0735.0
15184.75401.756864.752540.75
161630.252681.252844.252836.25
PFM
ACGT
010.2550.1760.3420.227
020.2070.070.5680.155
030.1030.0340.6860.177
040.0620.0160.8220.1
050.5140.0920.2630.132
060.1330.8520.0090.006
070.0180.0140.9380.03
080.01.00.00.0
091.00.00.00.0
100.00.0040.9920.004
110.0140.9660.020.0
120.00.00.01.0
130.00.00.9990.0
140.1070.690.130.074
150.0180.040.6870.254
160.1630.2680.2850.284
PWM
ACGT
010.02-0.3490.312-0.096
02-0.188-1.2670.819-0.478
03-0.889-1.9831.009-0.346
04-1.388-2.7531.19-0.915
050.72-1.0020.05-0.641
06-0.6321.226-3.288-3.742
07-2.608-2.8881.322-2.109
08-6.991.385-6.63-6.156
091.386-6.99-6.99-6.63
10-6.99-4.0111.378-4.153
11-2.8521.351-2.529-6.99
12-6.99-6.63-6.991.386
13-6.63-6.991.385-5.983
14-0.8491.014-0.655-1.221
15-2.593-1.8231.010.017
16-0.4260.0710.130.127
Standard thresholds
P-value Threshold
0.001 -1.40499
0.0005 0.45956
0.0001 4.33416