HEN1.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HEN1.H12INVITRO.0.S.B
Gene (human)	NHLH1 (GeneCards)
Gene synonyms (human)	BHLHA35, HEN1
Gene (mouse)	Nhlh1
Gene synonyms (mouse)	Hen1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	vvCAGCTGMKnMhn
GC content	62.98%
Information content (bits; total / per base)	12.526 / 0.895
Data sources	HT-SELEX
Aligned words	6490

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 6 experiments	median	0.899	0.893	0.722	0.738	0.615	0.643
Non-Methyl HT-SELEX, 6 experiments	best	0.939	0.935	0.751	0.765	0.642	0.66

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.4
HGNC	HGNC:7817
MGI	MGI:98481
EntrezGene (human)	GeneID:4807 (SSTAR profile)
EntrezGene (mouse)	GeneID:18071 (SSTAR profile)
UniProt ID (human)	HEN1_HUMAN
UniProt ID (mouse)	HEN1_MOUSE
UniProt AC (human)	Q02575 (TFClass)
UniProt AC (mouse)	Q02576 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	6
Methyl-HT-SELEX	0

PCM	HEN1.H12INVITRO.0.S.B.pcm
PWM	HEN1.H12INVITRO.0.S.B.pwm
PFM	HEN1.H12INVITRO.0.S.B.pfm
Alignment	HEN1.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	HEN1.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	HEN1.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	HEN1.H12INVITRO.0.S.B_meme_format.meme
Transfac format	HEN1.H12INVITRO.0.S.B_transfac_format.txt
Homer format	HEN1.H12INVITRO.0.S.B_homer_format_0.001.txt HEN1.H12INVITRO.0.S.B_homer_format_0.0005.txt HEN1.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1759.75	2765.75	1186.75	777.75
02	996.25	1239.25	3337.25	917.25
03	162.0	6004.0	104.0	220.0
04	6304.0	54.0	32.0	100.0
05	14.0	589.0	5379.0	508.0
06	96.0	6209.0	184.0	1.0
07	1.0	0.0	0.0	6489.0
08	31.0	24.0	6335.0	100.0
09	880.0	4667.0	325.0	618.0
10	255.0	359.0	3437.0	2439.0
11	1287.0	2122.0	961.0	2120.0
12	1041.0	4101.0	319.0	1029.0
13	1263.5	3329.5	630.5	1266.5
14	1505.5	2366.5	1163.5	1454.5

PFM

	A	C	G	T
01	0.271	0.426	0.183	0.12
02	0.154	0.191	0.514	0.141
03	0.025	0.925	0.016	0.034
04	0.971	0.008	0.005	0.015
05	0.002	0.091	0.829	0.078
06	0.015	0.957	0.028	0.0
07	0.0	0.0	0.0	1.0
08	0.005	0.004	0.976	0.015
09	0.136	0.719	0.05	0.095
10	0.039	0.055	0.53	0.376
11	0.198	0.327	0.148	0.327
12	0.16	0.632	0.049	0.159
13	0.195	0.513	0.097	0.195
14	0.232	0.365	0.179	0.224

PWM

	A	C	G	T
01	0.081	0.533	-0.312	-0.734
02	-0.487	-0.269	0.72	-0.569
03	-2.292	1.307	-2.728	-1.99
04	1.356	-3.364	-3.861	-2.766
05	-4.608	-1.011	1.198	-1.158
06	-2.806	1.341	-2.166	-6.232
07	-6.232	-6.607	-6.607	1.385
08	-3.891	-4.128	1.361	-2.766
09	-0.611	1.056	-1.603	-0.963
10	-1.843	-1.504	0.75	0.407
11	-0.231	0.268	-0.523	0.267
12	-0.443	0.926	-1.621	-0.455
13	-0.25	0.718	-0.943	-0.247
14	-0.075	0.377	-0.332	-0.109

Standard thresholds

P-value	Threshold
0.001	3.80636
0.0005	4.92576
0.0001	7.18901