MotifHEN1.H12CORE.0.S.B
Gene (human)NHLH1
(GeneCards)
Gene synonyms (human)BHLHA35, HEN1
Gene (mouse)Nhlh1
Gene synonyms (mouse)Hen1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusvvCAGCTGMKnMhn
GC content62.98%
Information content (bits; total / per base)12.526 / 0.895
Data sourcesHT-SELEX
Aligned words6490

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 6 experiments median 0.899 0.893 0.722 0.738 0.615 0.643
best 0.939 0.935 0.751 0.765 0.642 0.66
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyTAL-HEN {1.2.3.1} (TFClass)
TFClass IDTFClass: 1.2.3.1.4
HGNCHGNC:7817
MGIMGI:98481
EntrezGene (human)GeneID:4807
(SSTAR profile)
EntrezGene (mouse)GeneID:18071
(SSTAR profile)
UniProt ID (human)HEN1_HUMAN
UniProt ID (mouse)HEN1_MOUSE
UniProt AC (human)Q02575
(TFClass)
UniProt AC (mouse)Q02576
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 0
PCM
ACGT
011759.752765.751186.75777.75
02996.251239.253337.25917.25
03162.06004.0104.0220.0
046304.054.032.0100.0
0514.0589.05379.0508.0
0696.06209.0184.01.0
071.00.00.06489.0
0831.024.06335.0100.0
09880.04667.0325.0618.0
10255.0359.03437.02439.0
111287.02122.0961.02120.0
121041.04101.0319.01029.0
131263.53329.5630.51266.5
141505.52366.51163.51454.5
PFM
ACGT
010.2710.4260.1830.12
020.1540.1910.5140.141
030.0250.9250.0160.034
040.9710.0080.0050.015
050.0020.0910.8290.078
060.0150.9570.0280.0
070.00.00.01.0
080.0050.0040.9760.015
090.1360.7190.050.095
100.0390.0550.530.376
110.1980.3270.1480.327
120.160.6320.0490.159
130.1950.5130.0970.195
140.2320.3650.1790.224
PWM
ACGT
010.0810.533-0.312-0.734
02-0.487-0.2690.72-0.569
03-2.2921.307-2.728-1.99
041.356-3.364-3.861-2.766
05-4.608-1.0111.198-1.158
06-2.8061.341-2.166-6.232
07-6.232-6.607-6.6071.385
08-3.891-4.1281.361-2.766
09-0.6111.056-1.603-0.963
10-1.843-1.5040.750.407
11-0.2310.268-0.5230.267
12-0.4430.926-1.621-0.455
13-0.250.718-0.943-0.247
14-0.0750.377-0.332-0.109
Standard thresholds
P-value Threshold
0.001 3.80636
0.0005 4.92576
0.0001 7.18901