MotifHAND2.H12INVIVO.1.P.B
Gene (human)HAND2
(GeneCards)
Gene synonyms (human)BHLHA26, DHAND
Gene (mouse)Hand2
Gene synonyms (mouse)Dhand, Hed, Thing2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusvdKSYCTGGnhdbb
GC content61.3%
Information content (bits; total / per base)10.162 / 0.726
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (26) 0.754 0.786 0.581 0.618 0.698 0.783 1.847 2.293 51.891 85.125
Mouse 1 (7) 0.703 0.73 0.542 0.568 0.694 0.705 1.834 1.862 23.62 40.174

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.43 0.462 0.46 0.474 0.484 0.485
best 0.43 0.462 0.46 0.474 0.484 0.485
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyTWIST {1.2.3.2} (TFClass)
TFClass IDTFClass: 1.2.3.2.4
HGNCHGNC:4808
MGIMGI:103580
EntrezGene (human)GeneID:9464
(SSTAR profile)
EntrezGene (mouse)GeneID:15111
(SSTAR profile)
UniProt ID (human)HAND2_HUMAN
UniProt ID (mouse)HAND2_MOUSE
UniProt AC (human)P61296
(TFClass)
UniProt AC (mouse)Q61039
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
01187.0286.0392.0135.0
02320.039.0455.0186.0
03112.0117.0631.0140.0
0443.0286.0625.046.0
0528.0480.045.0447.0
0612.0970.015.03.0
072.01.00.0997.0
081.02.0995.02.0
093.0107.0840.050.0
10268.0361.0169.0202.0
11255.0277.097.0371.0
12216.056.0166.0562.0
1358.0275.0383.0284.0
1456.0365.0147.0432.0
PFM
ACGT
010.1870.2860.3920.135
020.320.0390.4550.186
030.1120.1170.6310.14
040.0430.2860.6250.046
050.0280.480.0450.447
060.0120.970.0150.003
070.0020.0010.00.997
080.0010.0020.9950.002
090.0030.1070.840.05
100.2680.3610.1690.202
110.2550.2770.0970.371
120.2160.0560.1660.562
130.0580.2750.3830.284
140.0560.3650.1470.432
PWM
ACGT
01-0.2880.1340.447-0.61
020.245-1.8210.596-0.293
03-0.795-0.7520.922-0.574
04-1.7280.1340.912-1.663
05-2.1360.649-1.6840.578
06-2.9091.351-2.711-3.975
07-4.213-4.525-4.9821.378
08-4.525-4.2131.376-4.213
09-3.975-0.841.207-1.582
100.0690.365-0.388-0.212
110.020.102-0.9360.393
12-0.145-1.473-0.4060.806
13-1.4390.0950.4240.127
14-1.4730.376-0.5260.544
Standard thresholds
P-value Threshold
0.001 4.81871
0.0005 5.72781
0.0001 7.42411