MotifHAND2.H12INVITRO.2.S.C
Gene (human)HAND2
(GeneCards)
Gene synonyms (human)BHLHA26, DHAND
Gene (mouse)Hand2
Gene synonyms (mouse)Dhand, Hed, Thing2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length12
ConsensusnhRCACCTGYdh
GC content59.74%
Information content (bits; total / per base)13.72 / 1.143
Data sourcesHT-SELEX
Aligned words428

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (26) 0.48 0.494 0.318 0.331 0.514 0.54 1.013 1.118 3.151 6.108
Mouse 1 (7) 0.502 0.508 0.342 0.349 0.52 0.542 1.046 1.11 1.824 3.201

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 1 experiments median 0.827 0.807 0.672 0.678 0.588 0.606
best 0.827 0.807 0.672 0.678 0.588 0.606
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyTWIST {1.2.3.2} (TFClass)
TFClass IDTFClass: 1.2.3.2.4
HGNCHGNC:4808
MGIMGI:103580
EntrezGene (human)GeneID:9464
(SSTAR profile)
EntrezGene (mouse)GeneID:15111
(SSTAR profile)
UniProt ID (human)HAND2_HUMAN
UniProt ID (mouse)HAND2_MOUSE
UniProt AC (human)P61296
(TFClass)
UniProt AC (mouse)Q61039
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 0
PCM
ACGT
0189.093.0149.097.0
02149.25114.2518.25146.25
03172.051.0202.03.0
040.0428.00.00.0
05428.00.00.00.0
060.0428.00.00.0
070.0428.00.00.0
080.00.00.0428.0
091.00.0427.00.0
104.0284.054.086.0
11182.7562.7591.7590.75
1290.75175.7561.7599.75
PFM
ACGT
010.2080.2170.3480.227
020.3490.2670.0430.342
030.4020.1190.4720.007
040.01.00.00.0
051.00.00.00.0
060.01.00.00.0
070.01.00.00.0
080.00.00.01.0
090.0020.00.9980.0
100.0090.6640.1260.201
110.4270.1470.2140.212
120.2120.4110.1440.233
PWM
ACGT
01-0.181-0.1380.327-0.097
020.3290.065-1.7030.309
030.469-0.7260.629-3.18
04-4.2721.376-4.272-4.272
051.376-4.272-4.272-4.272
06-4.2721.376-4.272-4.272
07-4.2721.376-4.272-4.272
08-4.272-4.272-4.2721.376
09-3.765-4.2721.373-4.272
10-2.9790.967-0.67-0.215
110.529-0.524-0.151-0.162
12-0.1620.491-0.54-0.069
Standard thresholds
P-value Threshold
0.001 3.073125
0.0005 4.00444
0.0001 7.200495