HAND1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HAND1.H12CORE.0.P.B
Gene (human)	HAND1 (GeneCards)
Gene synonyms (human)	BHLHA27, EHAND
Gene (mouse)	Hand1
Gene synonyms (mouse)	Ehand, Hxt, Thing1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	dbvYCTGSnhhnbvTCW
GC content	54.43%
Information content (bits; total / per base)	10.89 / 0.641
Data sources	ChIP-Seq
Aligned words	1005

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.788	0.874	0.719	0.808	0.763	0.861	2.893	3.547	60.06	147.824
Mouse	1 (7)	0.901	0.903	0.836	0.846	0.884	0.89	3.604	3.679	257.959	303.149

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TWIST {1.2.3.2} (TFClass)
TFClass ID	TFClass: 1.2.3.2.3
HGNC	HGNC:4807
MGI	MGI:103577
EntrezGene (human)	GeneID:9421 (SSTAR profile)
EntrezGene (mouse)	GeneID:15110 (SSTAR profile)
UniProt ID (human)	HAND1_HUMAN
UniProt ID (mouse)	HAND1_MOUSE
UniProt AC (human)	O96004 (TFClass)
UniProt AC (mouse)	Q64279 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	HAND1.H12CORE.0.P.B.pcm
PWM	HAND1.H12CORE.0.P.B.pwm
PFM	HAND1.H12CORE.0.P.B.pfm
Alignment	HAND1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	HAND1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	HAND1.H12CORE.0.P.B_jaspar_format.txt
MEME format	HAND1.H12CORE.0.P.B_meme_format.meme
Transfac format	HAND1.H12CORE.0.P.B_transfac_format.txt
Homer format	HAND1.H12CORE.0.P.B_homer_format_0.001.txt HAND1.H12CORE.0.P.B_homer_format_0.0005.txt HAND1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	241.0	123.0	453.0	188.0
02	113.0	205.0	513.0	174.0
03	141.0	198.0	536.0	130.0
04	42.0	406.0	78.0	479.0
05	10.0	975.0	10.0	10.0
06	8.0	17.0	3.0	977.0
07	5.0	10.0	979.0	11.0
08	9.0	221.0	625.0	150.0
09	255.0	225.0	173.0	352.0
10	194.0	232.0	121.0	458.0
11	237.0	185.0	143.0	440.0
12	201.0	264.0	237.0	303.0
13	55.0	379.0	99.0	472.0
14	202.0	274.0	396.0	133.0
15	15.0	50.0	84.0	856.0
16	36.0	862.0	40.0	67.0
17	588.0	159.0	25.0	233.0

PFM

	A	C	G	T
01	0.24	0.122	0.451	0.187
02	0.112	0.204	0.51	0.173
03	0.14	0.197	0.533	0.129
04	0.042	0.404	0.078	0.477
05	0.01	0.97	0.01	0.01
06	0.008	0.017	0.003	0.972
07	0.005	0.01	0.974	0.011
08	0.009	0.22	0.622	0.149
09	0.254	0.224	0.172	0.35
10	0.193	0.231	0.12	0.456
11	0.236	0.184	0.142	0.438
12	0.2	0.263	0.236	0.301
13	0.055	0.377	0.099	0.47
14	0.201	0.273	0.394	0.132
15	0.015	0.05	0.084	0.852
16	0.036	0.858	0.04	0.067
17	0.585	0.158	0.025	0.232

PWM

	A	C	G	T
01	-0.041	-0.707	0.586	-0.288
02	-0.791	-0.202	0.71	-0.364
03	-0.572	-0.236	0.754	-0.653
04	-1.755	0.477	-1.155	0.642
05	-3.071	1.351	-3.071	-3.071
06	-3.258	-2.603	-3.98	1.353
07	-3.627	-3.071	1.355	-2.989
08	-3.16	-0.127	0.907	-0.511
09	0.015	-0.11	-0.37	0.335
10	-0.257	-0.079	-0.723	0.597
11	-0.058	-0.304	-0.558	0.557
12	-0.221	0.049	-0.058	0.186
13	-1.495	0.409	-0.921	0.627
14	-0.217	0.086	0.452	-0.63
15	-2.716	-1.587	-1.082	1.221
16	-1.903	1.228	-1.802	-1.303
17	0.846	-0.454	-2.248	-0.075

Standard thresholds

P-value	Threshold
0.001	4.52146
0.0005	5.43506
0.0001	7.29981