MotifGSC2.H12RSNP.0.SM.D
Gene (human)GSC2
(GeneCards)
Gene synonyms (human)GSCL
Gene (mouse)Gsc2
Gene synonyms (mouse)Gscl
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length9
ConsensusnvRATTAdn
GC content35.87%
Information content (bits; total / per base)8.044 / 0.894
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8964

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.773 0.727 0.683 0.658 0.591 0.597
best 0.916 0.87 0.896 0.845 0.816 0.78
Methyl HT-SELEX, 1 experiments median 0.861 0.812 0.754 0.722 0.631 0.639
best 0.861 0.812 0.754 0.722 0.631 0.639
Non-Methyl HT-SELEX, 3 experiments median 0.686 0.643 0.613 0.593 0.55 0.555
best 0.916 0.87 0.896 0.845 0.816 0.78
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyGSC {3.1.3.9} (TFClass)
TFClass IDTFClass: 3.1.3.9.2
HGNCHGNC:4613
MGIMGI:892006
EntrezGene (human)GeneID:2928
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)GSC2_HUMAN
UniProt ID (mouse)GSC2_MOUSE
UniProt AC (human)O15499
(TFClass)
UniProt AC (mouse)P56916
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012462.02473.02640.01389.0
021780.751801.754151.751229.75
031414.0764.06553.0233.0
048392.0529.043.00.0
050.00.051.08913.0
060.095.0149.08720.0
078286.0106.0234.0338.0
082927.251099.253331.251606.25
091573.752280.752635.752473.75
PFM
ACGT
010.2750.2760.2950.155
020.1990.2010.4630.137
030.1580.0850.7310.026
040.9360.0590.0050.0
050.00.00.0060.994
060.00.0110.0170.973
070.9240.0120.0260.038
080.3270.1230.3720.179
090.1760.2540.2940.276
PWM
ACGT
010.0940.0980.164-0.478
02-0.23-0.2180.616-0.599
03-0.46-1.0741.072-2.255
041.32-1.44-3.903-6.894
05-6.894-6.894-3.741.38
06-6.894-3.138-2.6971.358
071.307-3.031-2.251-1.886
080.267-0.7110.396-0.333
09-0.3530.0180.1620.099
Standard thresholds
P-value Threshold
0.001 5.399405
0.0005 6.17428
0.0001 7.02838