MotifGSC.H12RSNP.0.SM.B
Gene (human)GSC
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gsc
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusnKGATTAdb
GC content39.74%
Information content (bits; total / per base)9.793 / 1.088
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9364

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.92 0.874 0.886 0.836 0.843 0.793
best 0.987 0.98 0.98 0.968 0.961 0.944
Methyl HT-SELEX, 2 experiments median 0.961 0.937 0.939 0.91 0.902 0.87
best 0.985 0.976 0.975 0.961 0.945 0.926
Non-Methyl HT-SELEX, 4 experiments median 0.841 0.798 0.767 0.732 0.704 0.682
best 0.987 0.98 0.98 0.968 0.961 0.944

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.748 0.605 0.765 0.563
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyGSC {3.1.3.9} (TFClass)
TFClass IDTFClass: 3.1.3.9.1
HGNCHGNC:4612
MGIMGI:95841
EntrezGene (human)GeneID:145258
(SSTAR profile)
EntrezGene (mouse)GeneID:14836
(SSTAR profile)
UniProt ID (human)GSC_HUMAN
UniProt ID (mouse)GSC_MOUSE
UniProt AC (human)P56915
(TFClass)
UniProt AC (mouse)Q02591
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012072.02789.02842.01661.0
021076.0762.05926.01600.0
03208.0199.08947.010.0
048984.0380.00.00.0
050.00.00.09364.0
066.0565.00.08793.0
079313.06.06.039.0
083023.51407.53501.51431.5
091212.753513.752648.751988.75
PFM
ACGT
010.2210.2980.3040.177
020.1150.0810.6330.171
030.0220.0210.9550.001
040.9590.0410.00.0
050.00.00.01.0
060.0010.060.00.939
070.9950.0010.0010.004
080.3230.150.3740.153
090.130.3750.2830.212
PWM
ACGT
01-0.1220.1750.194-0.343
02-0.776-1.120.928-0.38
03-2.411-2.4551.34-5.251
041.344-1.813-6.932-6.932
05-6.932-6.932-6.9321.386
06-5.645-1.418-6.9321.323
071.38-5.645-5.645-4.039
080.256-0.5080.402-0.491
09-0.6570.4060.123-0.163
Standard thresholds
P-value Threshold
0.001 5.03364
0.0005 6.12997
0.0001 7.63352