| Motif | GSC.H12INVIVO.0.SM.D |
| Gene (human) | GSC (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Gsc |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | GSC.H12INVIVO.0.SM.D |
| Gene (human) | GSC (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Gsc |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 10 |
| Consensus | nbGATTAnbn |
| GC content | 41.96% |
| Information content (bits; total / per base) | 9.321 / 0.932 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8700 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.926 | 0.883 | 0.892 | 0.845 | 0.848 | 0.8 |
| best | 0.989 | 0.982 | 0.983 | 0.972 | 0.965 | 0.951 | |
| Methyl HT-SELEX, 2 experiments | median | 0.964 | 0.941 | 0.943 | 0.916 | 0.906 | 0.875 |
| best | 0.986 | 0.978 | 0.977 | 0.964 | 0.948 | 0.931 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.847 | 0.805 | 0.772 | 0.739 | 0.708 | 0.687 |
| best | 0.989 | 0.982 | 0.983 | 0.972 | 0.965 | 0.951 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.742 | 0.601 | 0.763 | 0.558 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | GSC {3.1.3.9} (TFClass) |
| TFClass ID | TFClass: 3.1.3.9.1 |
| HGNC | HGNC:4612 |
| MGI | MGI:95841 |
| EntrezGene (human) | GeneID:145258 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:14836 (SSTAR profile) |
| UniProt ID (human) | GSC_HUMAN |
| UniProt ID (mouse) | GSC_MOUSE |
| UniProt AC (human) | P56915 (TFClass) |
| UniProt AC (mouse) | Q02591 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | GSC.H12INVIVO.0.SM.D.pcm |
| PWM | GSC.H12INVIVO.0.SM.D.pwm |
| PFM | GSC.H12INVIVO.0.SM.D.pfm |
| Alignment | GSC.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | GSC.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | GSC.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | GSC.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | GSC.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1939.25 | 2602.25 | 2682.25 | 1476.25 |
| 02 | 1218.5 | 1433.5 | 4587.5 | 1460.5 |
| 03 | 300.0 | 237.0 | 8149.0 | 14.0 |
| 04 | 8276.0 | 424.0 | 0.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 8700.0 |
| 06 | 38.0 | 640.0 | 1.0 | 8021.0 |
| 07 | 8620.0 | 2.0 | 17.0 | 61.0 |
| 08 | 2387.0 | 1518.0 | 3204.0 | 1591.0 |
| 09 | 1006.75 | 3484.75 | 2544.75 | 1663.75 |
| 10 | 1654.75 | 2396.75 | 2581.75 | 2066.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.223 | 0.299 | 0.308 | 0.17 |
| 02 | 0.14 | 0.165 | 0.527 | 0.168 |
| 03 | 0.034 | 0.027 | 0.937 | 0.002 |
| 04 | 0.951 | 0.049 | 0.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.004 | 0.074 | 0.0 | 0.922 |
| 07 | 0.991 | 0.0 | 0.002 | 0.007 |
| 08 | 0.274 | 0.174 | 0.368 | 0.183 |
| 09 | 0.116 | 0.401 | 0.293 | 0.191 |
| 10 | 0.19 | 0.275 | 0.297 | 0.238 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.115 | 0.179 | 0.209 | -0.387 |
| 02 | -0.579 | -0.416 | 0.746 | -0.398 |
| 03 | -1.975 | -2.208 | 1.32 | -4.897 |
| 04 | 1.336 | -1.631 | -6.867 | -6.867 |
| 05 | -6.867 | -6.867 | -6.867 | 1.386 |
| 06 | -3.99 | -1.221 | -6.502 | 1.304 |
| 07 | 1.376 | -6.235 | -4.727 | -3.538 |
| 08 | 0.093 | -0.359 | 0.387 | -0.312 |
| 09 | -0.769 | 0.471 | 0.157 | -0.268 |
| 10 | -0.273 | 0.097 | 0.171 | -0.051 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.183555 |
| 0.0005 | 6.29622 |
| 0.0001 | 7.47939 |