MotifGSC.H12CORE.0.SM.B
Gene (human)GSC
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gsc
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnbGATTAnbn
GC content41.96%
Information content (bits; total / per base)9.321 / 0.932
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8700

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.926 0.883 0.892 0.845 0.848 0.8
best 0.989 0.982 0.983 0.972 0.965 0.951
Methyl HT-SELEX, 2 experiments median 0.964 0.941 0.943 0.916 0.906 0.875
best 0.986 0.978 0.977 0.964 0.948 0.931
Non-Methyl HT-SELEX, 4 experiments median 0.847 0.805 0.772 0.739 0.708 0.687
best 0.989 0.982 0.983 0.972 0.965 0.951

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.742 0.601 0.763 0.558
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyGSC {3.1.3.9} (TFClass)
TFClass IDTFClass: 3.1.3.9.1
HGNCHGNC:4612
MGIMGI:95841
EntrezGene (human)GeneID:145258
(SSTAR profile)
EntrezGene (mouse)GeneID:14836
(SSTAR profile)
UniProt ID (human)GSC_HUMAN
UniProt ID (mouse)GSC_MOUSE
UniProt AC (human)P56915
(TFClass)
UniProt AC (mouse)Q02591
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
011939.252602.252682.251476.25
021218.51433.54587.51460.5
03300.0237.08149.014.0
048276.0424.00.00.0
050.00.00.08700.0
0638.0640.01.08021.0
078620.02.017.061.0
082387.01518.03204.01591.0
091006.753484.752544.751663.75
101654.752396.752581.752066.75
PFM
ACGT
010.2230.2990.3080.17
020.140.1650.5270.168
030.0340.0270.9370.002
040.9510.0490.00.0
050.00.00.01.0
060.0040.0740.00.922
070.9910.00.0020.007
080.2740.1740.3680.183
090.1160.4010.2930.191
100.190.2750.2970.238
PWM
ACGT
01-0.1150.1790.209-0.387
02-0.579-0.4160.746-0.398
03-1.975-2.2081.32-4.897
041.336-1.631-6.867-6.867
05-6.867-6.867-6.8671.386
06-3.99-1.221-6.5021.304
071.376-6.235-4.727-3.538
080.093-0.3590.387-0.312
09-0.7690.4710.157-0.268
10-0.2730.0970.171-0.051
Standard thresholds
P-value Threshold
0.001 5.183555
0.0005 6.29622
0.0001 7.47939