GRHL2.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GRHL2.H12RSNP.0.P.B
Gene (human)	GRHL2 (GeneCards)
Gene synonyms (human)	BOM, TFCP2L3
Gene (mouse)	Grhl2
Gene synonyms (mouse)	Bom, Tcfcp2l3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	CYKGTTbddChRG
GC content	58.02%
Information content (bits; total / per base)	11.91 / 0.916
Data sources	ChIP-Seq
Aligned words	950

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	23 (153)	0.937	0.967	0.882	0.942	0.89	0.93	3.163	3.695	594.569	672.495
Mouse	4 (28)	0.889	0.933	0.839	0.87	0.831	0.88	2.935	3.156	353.602	650.357

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.618	9.993	0.405	0.281

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	Grainyhead-related {6.7.1} (TFClass)
TF subfamily	GRH-like {6.7.1.1} (TFClass)
TFClass ID	TFClass: 6.7.1.1.2
HGNC	HGNC:2799
MGI	MGI:2182543
EntrezGene (human)	GeneID:79977 (SSTAR profile)
EntrezGene (mouse)	GeneID:252973 (SSTAR profile)
UniProt ID (human)	GRHL2_HUMAN
UniProt ID (mouse)	GRHL2_MOUSE
UniProt AC (human)	Q6ISB3 (TFClass)
UniProt AC (mouse)	Q8K5C0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	23 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	GRHL2.H12RSNP.0.P.B.pcm
PWM	GRHL2.H12RSNP.0.P.B.pwm
PFM	GRHL2.H12RSNP.0.P.B.pfm
Alignment	GRHL2.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	GRHL2.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	GRHL2.H12RSNP.0.P.B_jaspar_format.txt
MEME format	GRHL2.H12RSNP.0.P.B_meme_format.meme
Transfac format	GRHL2.H12RSNP.0.P.B_transfac_format.txt
Homer format	GRHL2.H12RSNP.0.P.B_homer_format_0.001.txt GRHL2.H12RSNP.0.P.B_homer_format_0.0005.txt GRHL2.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1.0	944.0	3.0	2.0
02	187.0	503.0	14.0	246.0
03	189.0	12.0	497.0	252.0
04	1.0	2.0	916.0	31.0
05	8.0	57.0	1.0	884.0
06	7.0	226.0	5.0	712.0
07	83.0	205.0	111.0	551.0
08	105.0	59.0	458.0	328.0
09	248.0	62.0	398.0	242.0
10	4.0	896.0	26.0	24.0
11	307.0	408.0	49.0	186.0
12	419.0	5.0	371.0	155.0
13	6.0	144.0	793.0	7.0

PFM

	A	C	G	T
01	0.001	0.994	0.003	0.002
02	0.197	0.529	0.015	0.259
03	0.199	0.013	0.523	0.265
04	0.001	0.002	0.964	0.033
05	0.008	0.06	0.001	0.931
06	0.007	0.238	0.005	0.749
07	0.087	0.216	0.117	0.58
08	0.111	0.062	0.482	0.345
09	0.261	0.065	0.419	0.255
10	0.004	0.943	0.027	0.025
11	0.323	0.429	0.052	0.196
12	0.441	0.005	0.391	0.163
13	0.006	0.152	0.835	0.007

PWM

	A	C	G	T
01	-4.479	1.375	-3.927	-4.165
02	-0.237	0.747	-2.723	0.035
03	-0.227	-2.859	0.735	0.059
04	-4.479	-4.165	1.345	-1.99
05	-3.204	-1.405	-4.479	1.309
06	-3.312	-0.049	-3.573	1.093
07	-1.038	-0.146	-0.753	0.837
08	-0.807	-1.371	0.653	0.321
09	0.043	-1.323	0.513	0.019
10	-3.734	1.322	-2.155	-2.23
11	0.255	0.538	-1.551	-0.242
12	0.565	-3.573	0.443	-0.423
13	-3.434	-0.496	1.201	-3.312

Standard thresholds

P-value	Threshold
0.001	4.10506
0.0005	5.15516
0.0001	7.35508