GRHL2.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GRHL2.H12INVIVO.1.P.B
Gene (human)	GRHL2 (GeneCards)
Gene synonyms (human)	BOM, TFCP2L3
Gene (mouse)	Grhl2
Gene synonyms (mouse)	Bom, Tcfcp2l3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	vRRChGGTYYKdY
GC content	47.88%
Information content (bits; total / per base)	10.522 / 0.809
Data sources	ChIP-Seq
Aligned words	116

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	23 (153)	0.878	0.909	0.792	0.84	0.819	0.868	2.82	3.364	438.658	560.824
Mouse	4 (28)	0.834	0.864	0.754	0.782	0.787	0.818	2.642	3.106	300.168	445.432

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.533	5.437	0.306	0.215

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	Grainyhead-related {6.7.1} (TFClass)
TF subfamily	GRH-like {6.7.1.1} (TFClass)
TFClass ID	TFClass: 6.7.1.1.2
HGNC	HGNC:2799
MGI	MGI:2182543
EntrezGene (human)	GeneID:79977 (SSTAR profile)
EntrezGene (mouse)	GeneID:252973 (SSTAR profile)
UniProt ID (human)	GRHL2_HUMAN
UniProt ID (mouse)	GRHL2_MOUSE
UniProt AC (human)	Q6ISB3 (TFClass)
UniProt AC (mouse)	Q8K5C0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	23 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	GRHL2.H12INVIVO.1.P.B.pcm
PWM	GRHL2.H12INVIVO.1.P.B.pwm
PFM	GRHL2.H12INVIVO.1.P.B.pfm
Alignment	GRHL2.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	GRHL2.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	GRHL2.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	GRHL2.H12INVIVO.1.P.B_meme_format.meme
Transfac format	GRHL2.H12INVIVO.1.P.B_transfac_format.txt
Homer format	GRHL2.H12INVIVO.1.P.B_homer_format_0.001.txt GRHL2.H12INVIVO.1.P.B_homer_format_0.0005.txt GRHL2.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	51.0	24.0	31.0	10.0
02	77.0	8.0	20.0	11.0
03	83.0	1.0	24.0	8.0
04	5.0	104.0	5.0	2.0
05	35.0	16.0	6.0	59.0
06	2.0	0.0	108.0	6.0
07	2.0	3.0	106.0	5.0
08	8.0	9.0	2.0	97.0
09	9.0	19.0	15.0	73.0
10	9.0	13.0	8.0	86.0
11	6.0	2.0	63.0	45.0
12	31.0	3.0	42.0	40.0
13	12.0	85.0	5.0	14.0

PFM

	A	C	G	T
01	0.44	0.207	0.267	0.086
02	0.664	0.069	0.172	0.095
03	0.716	0.009	0.207	0.069
04	0.043	0.897	0.043	0.017
05	0.302	0.138	0.052	0.509
06	0.017	0.0	0.931	0.052
07	0.017	0.026	0.914	0.043
08	0.069	0.078	0.017	0.836
09	0.078	0.164	0.129	0.629
10	0.078	0.112	0.069	0.741
11	0.052	0.017	0.543	0.388
12	0.267	0.026	0.362	0.345
13	0.103	0.733	0.043	0.121

PWM

	A	C	G	T
01	0.547	-0.181	0.064	-0.993
02	0.952	-1.19	-0.354	-0.907
03	1.026	-2.624	-0.181	-1.19
04	-1.585	1.248	-1.585	-2.248
05	0.181	-0.563	-1.435	0.69
06	-2.248	-3.235	1.286	-1.435
07	-2.248	-1.975	1.267	-1.585
08	-1.19	-1.086	-2.248	1.179
09	-1.086	-0.402	-0.623	0.899
10	-1.086	-0.755	-1.19	1.061
11	-1.435	-2.248	0.754	0.425
12	0.064	-1.975	0.358	0.311
13	-0.828	1.049	-1.585	-0.687

Standard thresholds

P-value	Threshold
0.001	4.72086
0.0005	5.50636
0.0001	7.14888