| Motif | GRHL1.H12INVIVO.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | GRHL1.H12INVIVO.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 21 |
| Consensus | RnvRAACMRGYhnddChRGhh |
| GC content | 51.39% |
| Information content (bits; total / per base) | 14.577 / 0.694 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1000 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.982 | 0.99 | 0.968 | 0.98 | 0.97 | 0.979 | 5.192 | 5.582 | 559.977 | 787.092 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.999 | 0.999 | 0.993 | 0.991 | 0.935 | 0.936 |
| best | 1.0 | 1.0 | 0.999 | 0.999 | 0.995 | 0.994 | |
| Methyl HT-SELEX, 2 experiments | median | 0.999 | 0.999 | 0.999 | 0.998 | 0.995 | 0.993 |
| best | 1.0 | 0.999 | 0.999 | 0.998 | 0.995 | 0.994 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.989 | 0.986 | 0.927 | 0.923 | 0.799 | 0.811 |
| best | 1.0 | 1.0 | 0.999 | 0.999 | 0.995 | 0.994 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.82 | 0.513 | 0.829 | 0.586 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | Grainyhead domain factors {6.7} (TFClass) |
| TF family | Grainyhead-related {6.7.1} (TFClass) |
| TF subfamily | GRH-like {6.7.1.1} (TFClass) |
| TFClass ID | TFClass: 6.7.1.1.1 |
| HGNC | HGNC:17923 |
| MGI | MGI:2182540 |
| EntrezGene (human) | GeneID:29841 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:195733 (SSTAR profile) |
| UniProt ID (human) | GRHL1_HUMAN |
| UniProt ID (mouse) | GRHL1_MOUSE |
| UniProt AC (human) | Q9NZI5 (TFClass) |
| UniProt AC (mouse) | Q921D9 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | GRHL1.H12INVIVO.0.PSM.A.pcm |
| PWM | GRHL1.H12INVIVO.0.PSM.A.pwm |
| PFM | GRHL1.H12INVIVO.0.PSM.A.pfm |
| Alignment | GRHL1.H12INVIVO.0.PSM.A.words.tsv |
| Threshold to P-value map | GRHL1.H12INVIVO.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | GRHL1.H12INVIVO.0.PSM.A_jaspar_format.txt |
| MEME format | GRHL1.H12INVIVO.0.PSM.A_meme_format.meme |
| Transfac format | GRHL1.H12INVIVO.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 185.0 | 124.0 | 599.0 | 92.0 |
| 02 | 273.0 | 362.0 | 189.0 | 176.0 |
| 03 | 404.0 | 297.0 | 210.0 | 89.0 |
| 04 | 546.0 | 89.0 | 327.0 | 38.0 |
| 05 | 838.0 | 5.0 | 134.0 | 23.0 |
| 06 | 939.0 | 2.0 | 52.0 | 7.0 |
| 07 | 0.0 | 998.0 | 1.0 | 1.0 |
| 08 | 273.0 | 489.0 | 12.0 | 226.0 |
| 09 | 229.0 | 26.0 | 559.0 | 186.0 |
| 10 | 0.0 | 0.0 | 1000.0 | 0.0 |
| 11 | 172.0 | 189.0 | 8.0 | 631.0 |
| 12 | 141.0 | 360.0 | 29.0 | 470.0 |
| 13 | 224.0 | 231.0 | 182.0 | 363.0 |
| 14 | 271.0 | 55.0 | 439.0 | 235.0 |
| 15 | 403.0 | 36.0 | 373.0 | 188.0 |
| 16 | 1.0 | 897.0 | 37.0 | 65.0 |
| 17 | 363.0 | 359.0 | 85.0 | 193.0 |
| 18 | 437.0 | 11.0 | 480.0 | 72.0 |
| 19 | 6.0 | 238.0 | 756.0 | 0.0 |
| 20 | 244.0 | 199.0 | 60.0 | 497.0 |
| 21 | 147.0 | 224.0 | 68.0 | 561.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.185 | 0.124 | 0.599 | 0.092 |
| 02 | 0.273 | 0.362 | 0.189 | 0.176 |
| 03 | 0.404 | 0.297 | 0.21 | 0.089 |
| 04 | 0.546 | 0.089 | 0.327 | 0.038 |
| 05 | 0.838 | 0.005 | 0.134 | 0.023 |
| 06 | 0.939 | 0.002 | 0.052 | 0.007 |
| 07 | 0.0 | 0.998 | 0.001 | 0.001 |
| 08 | 0.273 | 0.489 | 0.012 | 0.226 |
| 09 | 0.229 | 0.026 | 0.559 | 0.186 |
| 10 | 0.0 | 0.0 | 1.0 | 0.0 |
| 11 | 0.172 | 0.189 | 0.008 | 0.631 |
| 12 | 0.141 | 0.36 | 0.029 | 0.47 |
| 13 | 0.224 | 0.231 | 0.182 | 0.363 |
| 14 | 0.271 | 0.055 | 0.439 | 0.235 |
| 15 | 0.403 | 0.036 | 0.373 | 0.188 |
| 16 | 0.001 | 0.897 | 0.037 | 0.065 |
| 17 | 0.363 | 0.359 | 0.085 | 0.193 |
| 18 | 0.437 | 0.011 | 0.48 | 0.072 |
| 19 | 0.006 | 0.238 | 0.756 | 0.0 |
| 20 | 0.244 | 0.199 | 0.06 | 0.497 |
| 21 | 0.147 | 0.224 | 0.068 | 0.561 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.299 | -0.694 | 0.87 | -0.988 |
| 02 | 0.087 | 0.368 | -0.278 | -0.348 |
| 03 | 0.477 | 0.171 | -0.173 | -1.02 |
| 04 | 0.777 | -1.02 | 0.267 | -1.846 |
| 05 | 1.205 | -3.622 | -0.618 | -2.32 |
| 06 | 1.318 | -4.213 | -1.544 | -3.362 |
| 07 | -4.982 | 1.379 | -4.525 | -4.525 |
| 08 | 0.087 | 0.668 | -2.909 | -0.1 |
| 09 | -0.087 | -2.206 | 0.801 | -0.293 |
| 10 | -4.982 | -4.982 | 1.381 | -4.982 |
| 11 | -0.371 | -0.278 | -3.253 | 0.922 |
| 12 | -0.567 | 0.363 | -2.103 | 0.628 |
| 13 | -0.109 | -0.078 | -0.315 | 0.371 |
| 14 | 0.08 | -1.49 | 0.56 | -0.061 |
| 15 | 0.475 | -1.898 | 0.398 | -0.283 |
| 16 | -4.525 | 1.273 | -1.872 | -1.328 |
| 17 | 0.371 | 0.36 | -1.066 | -0.257 |
| 18 | 0.556 | -2.985 | 0.649 | -1.228 |
| 19 | -3.484 | -0.049 | 1.102 | -4.982 |
| 20 | -0.024 | -0.226 | -1.406 | 0.684 |
| 21 | -0.526 | -0.109 | -1.284 | 0.804 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.00766 |
| 0.0005 | 4.24681 |
| 0.0001 | 6.76051 |