MotifGRHL1.H12INVITRO.1.PS.A
Gene (human)GRHL1
(GeneCards)
Gene synonyms (human)LBP32, MGR, TFCP2L2
Gene (mouse)Grhl1
Gene synonyms (mouse)Mgr, Tcfcp2l2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length12
ConsensusnWAACCRGTWhn
GC content43.05%
Information content (bits; total / per base)12.716 / 1.06
Data sourcesChIP-Seq + HT-SELEX
Aligned words9744

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.843 0.865 0.747 0.776 0.787 0.815 2.513 2.729 290.955 417.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.996 0.994 0.989 0.984 0.921 0.919
best 1.0 1.0 0.997 0.996 0.99 0.987
Methyl HT-SELEX, 2 experiments median 0.996 0.994 0.989 0.984 0.961 0.952
best 0.997 0.995 0.992 0.989 0.976 0.969
Non-Methyl HT-SELEX, 6 experiments median 0.992 0.99 0.93 0.928 0.804 0.818
best 1.0 1.0 0.997 0.996 0.99 0.987

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.855 0.545 0.808 0.554
TF superclassImmunoglobulin fold {6} (TFClass)
TF classGrainyhead domain factors {6.7} (TFClass)
TF familyGrainyhead-related {6.7.1} (TFClass)
TF subfamilyGRH-like {6.7.1.1} (TFClass)
TFClass IDTFClass: 6.7.1.1.1
HGNCHGNC:17923
MGIMGI:2182540
EntrezGene (human)GeneID:29841
(SSTAR profile)
EntrezGene (mouse)GeneID:195733
(SSTAR profile)
UniProt ID (human)GRHL1_HUMAN
UniProt ID (mouse)GRHL1_MOUSE
UniProt AC (human)Q9NZI5
(TFClass)
UniProt AC (mouse)Q921D9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
013519.02018.01931.02276.0
027389.25440.25907.251007.25
038794.0165.0431.0354.0
049693.01.02.048.0
050.09744.00.00.0
060.09722.08.014.0
071907.03.06059.01775.0
085.061.09677.01.0
091362.0432.0188.07762.0
101645.01451.0290.06358.0
112022.51713.51022.54985.5
122926.251846.252228.252743.25
PFM
ACGT
010.3610.2070.1980.234
020.7580.0450.0930.103
030.9030.0170.0440.036
040.9950.00.00.005
050.01.00.00.0
060.00.9980.0010.001
070.1960.00.6220.182
080.0010.0060.9930.0
090.140.0440.0190.797
100.1690.1490.030.653
110.2080.1760.1050.512
120.30.1890.2290.282
PWM
ACGT
010.368-0.188-0.232-0.068
021.109-1.707-0.986-0.882
031.283-2.679-1.728-1.923
041.38-6.606-6.341-3.881
05-6.9681.386-6.968-6.968
06-6.9681.383-5.467-5.008
07-0.245-6.1320.911-0.316
08-5.812-3.6511.379-6.606
09-0.581-1.725-2.551.158
10-0.392-0.517-2.1210.959
11-0.186-0.351-0.8670.716
120.183-0.277-0.0890.119
Standard thresholds
P-value Threshold
0.001 3.40081
0.0005 4.78641
0.0001 7.308915