| Motif | GRHL1.H12CORE.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | GRHL1.H12CORE.0.PSM.A |
| Gene (human) | GRHL1 (GeneCards) |
| Gene synonyms (human) | LBP32, MGR, TFCP2L2 |
| Gene (mouse) | Grhl1 |
| Gene synonyms (mouse) | Mgr, Tcfcp2l2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 19 |
| Consensus | ndAACCKGTWhdWChdGhh |
| GC content | 46.45% |
| Information content (bits; total / per base) | 16.271 / 0.856 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9105 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.966 | 0.975 | 0.935 | 0.952 | 0.945 | 0.958 | 4.499 | 4.869 | 521.263 | 712.081 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.999 | 0.999 | 0.996 | 0.994 | 0.948 | 0.95 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.997 | 0.996 | |
| Methyl HT-SELEX, 2 experiments | median | 1.0 | 0.999 | 0.999 | 0.998 | 0.996 | 0.994 |
| best | 1.0 | 1.0 | 0.999 | 0.999 | 0.996 | 0.995 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.991 | 0.988 | 0.937 | 0.933 | 0.814 | 0.826 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.997 | 0.996 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.892 | 0.665 | 0.872 | 0.583 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | Grainyhead domain factors {6.7} (TFClass) |
| TF family | Grainyhead-related {6.7.1} (TFClass) |
| TF subfamily | GRH-like {6.7.1.1} (TFClass) |
| TFClass ID | TFClass: 6.7.1.1.1 |
| HGNC | HGNC:17923 |
| MGI | MGI:2182540 |
| EntrezGene (human) | GeneID:29841 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:195733 (SSTAR profile) |
| UniProt ID (human) | GRHL1_HUMAN |
| UniProt ID (mouse) | GRHL1_MOUSE |
| UniProt AC (human) | Q9NZI5 (TFClass) |
| UniProt AC (mouse) | Q921D9 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | GRHL1.H12CORE.0.PSM.A.pcm |
| PWM | GRHL1.H12CORE.0.PSM.A.pwm |
| PFM | GRHL1.H12CORE.0.PSM.A.pfm |
| Alignment | GRHL1.H12CORE.0.PSM.A.words.tsv |
| Threshold to P-value map | GRHL1.H12CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | GRHL1.H12CORE.0.PSM.A_jaspar_format.txt |
| MEME format | GRHL1.H12CORE.0.PSM.A_meme_format.meme |
| Transfac format | GRHL1.H12CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 3233.75 | 2219.75 | 1807.75 | 1843.75 |
| 02 | 4979.5 | 759.5 | 1914.5 | 1451.5 |
| 03 | 8161.0 | 47.0 | 494.0 | 403.0 |
| 04 | 8767.0 | 10.0 | 37.0 | 291.0 |
| 05 | 0.0 | 9100.0 | 4.0 | 1.0 |
| 06 | 1130.0 | 7320.0 | 33.0 | 622.0 |
| 07 | 951.0 | 76.0 | 6992.0 | 1086.0 |
| 08 | 6.0 | 3.0 | 9096.0 | 0.0 |
| 09 | 1293.0 | 274.0 | 38.0 | 7500.0 |
| 10 | 1774.0 | 999.0 | 118.0 | 6214.0 |
| 11 | 3288.0 | 1028.0 | 750.0 | 4039.0 |
| 12 | 4356.0 | 565.0 | 1596.0 | 2588.0 |
| 13 | 5428.0 | 310.0 | 1329.0 | 2038.0 |
| 14 | 120.0 | 8600.0 | 137.0 | 248.0 |
| 15 | 2041.0 | 4185.0 | 1229.0 | 1650.0 |
| 16 | 3097.0 | 677.0 | 3977.0 | 1354.0 |
| 17 | 141.0 | 718.0 | 8134.0 | 112.0 |
| 18 | 2129.0 | 1516.0 | 1039.0 | 4421.0 |
| 19 | 2096.75 | 1925.75 | 1292.75 | 3789.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.355 | 0.244 | 0.199 | 0.202 |
| 02 | 0.547 | 0.083 | 0.21 | 0.159 |
| 03 | 0.896 | 0.005 | 0.054 | 0.044 |
| 04 | 0.963 | 0.001 | 0.004 | 0.032 |
| 05 | 0.0 | 0.999 | 0.0 | 0.0 |
| 06 | 0.124 | 0.804 | 0.004 | 0.068 |
| 07 | 0.104 | 0.008 | 0.768 | 0.119 |
| 08 | 0.001 | 0.0 | 0.999 | 0.0 |
| 09 | 0.142 | 0.03 | 0.004 | 0.824 |
| 10 | 0.195 | 0.11 | 0.013 | 0.682 |
| 11 | 0.361 | 0.113 | 0.082 | 0.444 |
| 12 | 0.478 | 0.062 | 0.175 | 0.284 |
| 13 | 0.596 | 0.034 | 0.146 | 0.224 |
| 14 | 0.013 | 0.945 | 0.015 | 0.027 |
| 15 | 0.224 | 0.46 | 0.135 | 0.181 |
| 16 | 0.34 | 0.074 | 0.437 | 0.149 |
| 17 | 0.015 | 0.079 | 0.893 | 0.012 |
| 18 | 0.234 | 0.167 | 0.114 | 0.486 |
| 19 | 0.23 | 0.212 | 0.142 | 0.416 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.351 | -0.025 | -0.23 | -0.21 |
| 02 | 0.782 | -1.096 | -0.173 | -0.449 |
| 03 | 1.276 | -3.834 | -1.524 | -1.727 |
| 04 | 1.348 | -5.223 | -4.061 | -2.05 |
| 05 | -6.907 | 1.385 | -5.894 | -6.544 |
| 06 | -0.699 | 1.167 | -4.168 | -1.295 |
| 07 | -0.871 | -3.371 | 1.122 | -0.739 |
| 08 | -5.618 | -6.068 | 1.385 | -6.907 |
| 09 | -0.565 | -2.11 | -4.035 | 1.192 |
| 10 | -0.249 | -0.822 | -2.941 | 1.004 |
| 11 | 0.367 | -0.794 | -1.108 | 0.573 |
| 12 | 0.649 | -1.39 | -0.355 | 0.128 |
| 13 | 0.868 | -1.987 | -0.537 | -0.11 |
| 14 | -2.925 | 1.328 | -2.795 | -2.209 |
| 15 | -0.109 | 0.609 | -0.615 | -0.321 |
| 16 | 0.308 | -1.21 | 0.558 | -0.519 |
| 17 | -2.766 | -1.152 | 1.273 | -2.993 |
| 18 | -0.067 | -0.406 | -0.783 | 0.663 |
| 19 | -0.082 | -0.167 | -0.565 | 0.509 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.92876 |
| 0.0005 | 3.30806 |
| 0.0001 | 6.11476 |