GLIS3.H12INVIVO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GLIS3.H12INVIVO.1.S.C
Gene (human)	GLIS3 (GeneCards)
Gene synonyms (human)	ZNF515
Gene (mouse)	Glis3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	17
Consensus	nCdhYGYGGGGGGTvnn
GC content	69.15%
Information content (bits; total / per base)	16.837 / 0.99
Data sources	HT-SELEX
Aligned words	692

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.806	0.83	0.63	0.67	0.556	0.568	1.305	1.343	36.319	49.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.77	0.773	0.622	0.644	0.551	0.58
Non-Methyl HT-SELEX, 1 experiments	best	0.77	0.773	0.622	0.644	0.551	0.58

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.6
HGNC	HGNC:28510
MGI	MGI:2444289
EntrezGene (human)	GeneID:169792 (SSTAR profile)
EntrezGene (mouse)	GeneID:226075 (SSTAR profile)
UniProt ID (human)	GLIS3_HUMAN
UniProt ID (mouse)	GLIS3_MOUSE
UniProt AC (human)	Q8NEA6 (TFClass)
UniProt AC (mouse)	Q6XP49 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	GLIS3.H12INVIVO.1.S.C.pcm
PWM	GLIS3.H12INVIVO.1.S.C.pwm
PFM	GLIS3.H12INVIVO.1.S.C.pfm
Alignment	GLIS3.H12INVIVO.1.S.C.words.tsv
Threshold to P-value map	GLIS3.H12INVIVO.1.S.C.thr
Motif in other formats
JASPAR format	GLIS3.H12INVIVO.1.S.C_jaspar_format.txt
MEME format	GLIS3.H12INVIVO.1.S.C_meme_format.meme
Transfac format	GLIS3.H12INVIVO.1.S.C_transfac_format.txt
Homer format	GLIS3.H12INVIVO.1.S.C_homer_format_0.001.txt GLIS3.H12INVIVO.1.S.C_homer_format_0.0005.txt GLIS3.H12INVIVO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	148.5	142.5	234.5	166.5
02	21.5	609.5	49.5	11.5
03	132.0	42.0	230.0	288.0
04	116.0	252.0	61.0	263.0
05	49.0	340.0	52.0	251.0
06	37.0	42.0	605.0	8.0
07	16.0	239.0	65.0	372.0
08	4.0	0.0	685.0	3.0
09	1.0	0.0	677.0	14.0
10	0.0	0.0	692.0	0.0
11	1.0	0.0	691.0	0.0
12	0.0	0.0	686.0	6.0
13	3.0	3.0	654.0	32.0
14	12.0	54.0	64.0	562.0
15	252.0	312.0	93.0	35.0
16	221.25	86.25	170.25	214.25
17	171.75	127.75	175.75	216.75

PFM

	A	C	G	T
01	0.215	0.206	0.339	0.241
02	0.031	0.881	0.072	0.017
03	0.191	0.061	0.332	0.416
04	0.168	0.364	0.088	0.38
05	0.071	0.491	0.075	0.363
06	0.053	0.061	0.874	0.012
07	0.023	0.345	0.094	0.538
08	0.006	0.0	0.99	0.004
09	0.001	0.0	0.978	0.02
10	0.0	0.0	1.0	0.0
11	0.001	0.0	0.999	0.0
12	0.0	0.0	0.991	0.009
13	0.004	0.004	0.945	0.046
14	0.017	0.078	0.092	0.812
15	0.364	0.451	0.134	0.051
16	0.32	0.125	0.246	0.31
17	0.248	0.185	0.254	0.313

PWM

	A	C	G	T
01	-0.151	-0.192	0.302	-0.038
02	-2.021	1.253	-1.228	-2.587
03	-0.268	-1.387	0.282	0.506
04	-0.395	0.373	-1.025	0.416
05	-1.238	0.671	-1.18	0.369
06	-1.509	-1.387	1.245	-2.897
07	-2.293	0.321	-0.963	0.761
08	-3.434	-4.671	1.369	-3.629
09	-4.194	-4.671	1.357	-2.413
10	-4.671	-4.671	1.379	-4.671
11	-4.194	-4.671	1.378	-4.671
12	-4.671	-4.671	1.371	-3.13
13	-3.629	-3.629	1.323	-1.647
14	-2.55	-1.144	-0.979	1.172
15	0.373	0.586	-0.613	-1.562
16	0.244	-0.687	-0.016	0.212
17	-0.007	-0.3	0.016	0.224

Standard thresholds

P-value	Threshold
0.001	1.54291
0.0005	2.94391
0.0001	5.86601