GLIS3.H12CORE.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GLIS3.H12CORE.1.S.C
Gene (human)	GLIS3 (GeneCards)
Gene synonyms (human)	ZNF515
Gene (mouse)	Glis3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	12
Consensus	bSYGGGGGGKvn
GC content	72.94%
Information content (bits; total / per base)	12.081 / 1.007
Data sources	HT-SELEX
Aligned words	1618

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.793	0.811	0.61	0.636	0.542	0.558	1.271	1.316	34.824	43.208

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.793	0.782	0.639	0.654	0.565	0.588
Non-Methyl HT-SELEX, 1 experiments	best	0.793	0.782	0.639	0.654	0.565	0.588

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.6
HGNC	HGNC:28510
MGI	MGI:2444289
EntrezGene (human)	GeneID:169792 (SSTAR profile)
EntrezGene (mouse)	GeneID:226075 (SSTAR profile)
UniProt ID (human)	GLIS3_HUMAN
UniProt ID (mouse)	GLIS3_MOUSE
UniProt AC (human)	Q8NEA6 (TFClass)
UniProt AC (mouse)	Q6XP49 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	GLIS3.H12CORE.1.S.C.pcm
PWM	GLIS3.H12CORE.1.S.C.pwm
PFM	GLIS3.H12CORE.1.S.C.pfm
Alignment	GLIS3.H12CORE.1.S.C.words.tsv
Threshold to P-value map	GLIS3.H12CORE.1.S.C.thr
Motif in other formats
JASPAR format	GLIS3.H12CORE.1.S.C_jaspar_format.txt
MEME format	GLIS3.H12CORE.1.S.C_meme_format.meme
Transfac format	GLIS3.H12CORE.1.S.C_transfac_format.txt
Homer format	GLIS3.H12CORE.1.S.C_homer_format_0.001.txt GLIS3.H12CORE.1.S.C_homer_format_0.0005.txt GLIS3.H12CORE.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	205.0	680.0	215.0	518.0
02	149.25	232.25	1080.25	156.25
03	136.0	672.0	0.0	810.0
04	81.0	0.0	1519.0	18.0
05	34.0	58.0	1420.0	106.0
06	1.0	0.0	1606.0	11.0
07	19.0	2.0	1576.0	21.0
08	15.0	0.0	1603.0	0.0
09	51.0	0.0	1439.0	128.0
10	114.0	140.0	344.0	1020.0
11	557.75	576.75	282.75	200.75
12	472.5	266.5	450.5	428.5

PFM

	A	C	G	T
01	0.127	0.42	0.133	0.32
02	0.092	0.144	0.668	0.097
03	0.084	0.415	0.0	0.501
04	0.05	0.0	0.939	0.011
05	0.021	0.036	0.878	0.066
06	0.001	0.0	0.993	0.007
07	0.012	0.001	0.974	0.013
08	0.009	0.0	0.991	0.0
09	0.032	0.0	0.889	0.079
10	0.07	0.087	0.213	0.63
11	0.345	0.356	0.175	0.124
12	0.292	0.165	0.278	0.265

PWM

	A	C	G	T
01	-0.675	0.518	-0.628	0.246
02	-0.989	-0.551	0.979	-0.944
03	-1.081	0.506	-5.394	0.692
04	-1.59	-5.394	1.32	-3.019
05	-2.428	-1.915	1.253	-1.326
06	-4.961	-5.394	1.375	-3.454
07	-2.97	-4.66	1.357	-2.878
08	-3.183	-5.394	1.374	-5.394
09	-2.04	-5.394	1.266	-1.141
10	-1.255	-1.052	-0.161	0.922
11	0.32	0.353	-0.356	-0.696
12	0.155	-0.415	0.107	0.057

Standard thresholds

P-value	Threshold
0.001	4.00266
0.0005	5.10356
0.0001	7.31498