GLIS2.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GLIS2.H12INVIVO.0.SM.D
Gene (human)	GLIS2 (GeneCards)
Gene synonyms (human)	NKL
Gene (mouse)	Glis2
Gene synonyms (mouse)	Gli5, Nkl
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	16
Consensus	dShhYGYRGGGGGTvn
GC content	67.21%
Information content (bits; total / per base)	15.964 / 0.998
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9333

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.862	0.86	0.74	0.746	0.63	0.652
Overall, 4 experiments	best	0.997	0.995	0.954	0.954	0.717	0.775
Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.954	0.954	0.717	0.775
Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.954	0.954	0.717	0.775
Non-Methyl HT-SELEX, 3 experiments	median	0.758	0.77	0.616	0.64	0.553	0.579
Non-Methyl HT-SELEX, 3 experiments	best	0.966	0.95	0.864	0.851	0.707	0.725

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.5
HGNC	HGNC:29450
MGI	MGI:1932535
EntrezGene (human)	GeneID:84662 (SSTAR profile)
EntrezGene (mouse)	GeneID:83396 (SSTAR profile)
UniProt ID (human)	GLIS2_HUMAN
UniProt ID (mouse)	GLIS2_MOUSE
UniProt AC (human)	Q9BZE0 (TFClass)
UniProt AC (mouse)	Q8VDL9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	GLIS2.H12INVIVO.0.SM.D.pcm
PWM	GLIS2.H12INVIVO.0.SM.D.pwm
PFM	GLIS2.H12INVIVO.0.SM.D.pfm
Alignment	GLIS2.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	GLIS2.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	GLIS2.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	GLIS2.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	GLIS2.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	GLIS2.H12INVIVO.0.SM.D_homer_format_0.001.txt GLIS2.H12INVIVO.0.SM.D_homer_format_0.0005.txt GLIS2.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2302.75	1238.75	3471.75	2319.75
02	880.75	6476.75	1586.75	388.75
03	2826.0	982.0	832.0	4693.0
04	2059.0	2502.0	553.0	4219.0
05	358.0	5932.0	535.0	2508.0
06	1857.0	224.0	7180.0	72.0
07	316.0	4131.0	288.0	4598.0
08	1950.0	14.0	6325.0	1044.0
09	7.0	1.0	9180.0	145.0
10	1.0	0.0	9329.0	3.0
11	9.0	1.0	9322.0	1.0
12	1.0	0.0	9327.0	5.0
13	4.0	4.0	9268.0	57.0
14	2.0	566.0	773.0	7992.0
15	3143.5	4491.5	1382.5	315.5
16	2428.5	1672.5	2779.5	2452.5

PFM

	A	C	G	T
01	0.247	0.133	0.372	0.249
02	0.094	0.694	0.17	0.042
03	0.303	0.105	0.089	0.503
04	0.221	0.268	0.059	0.452
05	0.038	0.636	0.057	0.269
06	0.199	0.024	0.769	0.008
07	0.034	0.443	0.031	0.493
08	0.209	0.002	0.678	0.112
09	0.001	0.0	0.984	0.016
10	0.0	0.0	1.0	0.0
11	0.001	0.0	0.999	0.0
12	0.0	0.0	0.999	0.001
13	0.0	0.0	0.993	0.006
14	0.0	0.061	0.083	0.856
15	0.337	0.481	0.148	0.034
16	0.26	0.179	0.298	0.263

PWM

	A	C	G	T
01	-0.013	-0.632	0.397	-0.006
02	-0.973	1.02	-0.385	-1.787
03	0.191	-0.864	-1.029	0.698
04	-0.125	0.07	-1.437	0.592
05	-1.869	0.933	-1.469	0.072
06	-0.228	-2.334	1.123	-3.448
07	-1.993	0.571	-2.085	0.678
08	-0.179	-4.966	0.997	-0.803
09	-5.528	-6.567	1.369	-2.764
10	-6.567	-6.929	1.385	-6.091
11	-5.332	-6.567	1.384	-6.567
12	-6.567	-6.929	1.385	-5.77
13	-5.918	-5.918	1.379	-3.674
14	-6.301	-1.413	-1.103	1.23
15	0.298	0.654	-0.523	-1.995
16	0.04	-0.333	0.175	0.05

Standard thresholds

P-value	Threshold
0.001	0.73411
0.0005	2.40726
0.0001	5.93206