MotifGLIS1.H12INVIVO.2.SM.B
Gene (human)GLIS1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Glis1
Gene synonyms (mouse)Gli5
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length19
ConsensusnndCWhhGTGGGGGGTvdn
GC content63.94%
Information content (bits; total / per base)19.515 / 1.027
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8567

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (12) 0.779 0.819 0.589 0.656 0.68 0.687 1.697 1.749 51.722 79.509

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.97 0.961 0.892 0.888 0.769 0.783
best 0.999 0.998 0.986 0.983 0.885 0.887
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.986 0.983 0.885 0.887
best 0.999 0.998 0.986 0.983 0.885 0.887
Non-Methyl HT-SELEX, 1 experiments median 0.941 0.925 0.799 0.792 0.654 0.679
best 0.941 0.925 0.799 0.792 0.654 0.679

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.762 0.451 0.657 0.532
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.4
HGNCHGNC:29525
MGIMGI:2386723
EntrezGene (human)GeneID:148979
(SSTAR profile)
EntrezGene (mouse)GeneID:230587
(SSTAR profile)
UniProt ID (human)GLIS1_HUMAN
UniProt ID (mouse)GLIS1_MOUSE
UniProt AC (human)Q8NBF1
(TFClass)
UniProt AC (mouse)Q8K1M4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012099.251581.252589.252297.25
022602.51615.51958.52390.5
031562.0625.04302.02078.0
04296.07363.0789.0119.0
052686.0339.0643.04899.0
062130.02639.0289.03509.0
071655.04292.0660.01960.0
0838.092.08406.031.0
0936.0572.035.07924.0
10252.00.08298.017.0
110.01.08493.073.0
121.00.08564.02.0
13156.00.08395.016.0
142.00.08562.03.0
1538.05.08496.028.0
1615.0414.0561.07577.0
173928.02927.01577.0135.0
182497.5978.53388.51702.5
191752.251495.253139.252180.25
PFM
ACGT
010.2450.1850.3020.268
020.3040.1890.2290.279
030.1820.0730.5020.243
040.0350.8590.0920.014
050.3140.040.0750.572
060.2490.3080.0340.41
070.1930.5010.0770.229
080.0040.0110.9810.004
090.0040.0670.0040.925
100.0290.00.9690.002
110.00.00.9910.009
120.00.01.00.0
130.0180.00.980.002
140.00.00.9990.0
150.0040.0010.9920.003
160.0020.0480.0650.884
170.4590.3420.1840.016
180.2920.1140.3960.199
190.2050.1750.3660.254
PWM
ACGT
01-0.02-0.3030.190.07
020.195-0.282-0.0890.11
03-0.315-1.2290.697-0.03
04-1.9721.234-0.997-2.872
050.226-1.838-1.2010.827
06-0.0050.209-1.9960.493
07-0.2580.695-1.175-0.089
08-3.975-3.1241.367-4.166
09-4.026-1.317-4.0521.308
10-2.132-6.8531.354-4.712
11-6.853-6.4881.377-3.349
12-6.488-6.8531.385-6.22
13-2.606-6.8531.365-4.766
14-6.22-6.8531.385-6.01
15-3.975-5.6881.377-4.26
16-4.822-1.639-1.3371.263
170.6060.312-0.306-2.749
180.154-0.7820.458-0.229
19-0.2-0.3590.3820.018
Standard thresholds
P-value Threshold
0.001 -1.96499
0.0005 -0.13824
0.0001 3.67826