| Motif | GLIS1.H12INVITRO.2.SM.B |
| Gene (human) | GLIS1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Glis1 |
| Gene synonyms (mouse) | Gli5 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | GLIS1.H12INVITRO.2.SM.B |
| Gene (human) | GLIS1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Glis1 |
| Gene synonyms (mouse) | Gli5 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 19 |
| Consensus | nndCWhhGTGGGGGGTvdn |
| GC content | 63.94% |
| Information content (bits; total / per base) | 19.515 / 1.027 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8567 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (12) | 0.779 | 0.819 | 0.589 | 0.656 | 0.68 | 0.687 | 1.697 | 1.749 | 51.722 | 79.509 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.97 | 0.961 | 0.892 | 0.888 | 0.769 | 0.783 |
| best | 0.999 | 0.998 | 0.986 | 0.983 | 0.885 | 0.887 | |
| Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.998 | 0.986 | 0.983 | 0.885 | 0.887 |
| best | 0.999 | 0.998 | 0.986 | 0.983 | 0.885 | 0.887 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.941 | 0.925 | 0.799 | 0.792 | 0.654 | 0.679 |
| best | 0.941 | 0.925 | 0.799 | 0.792 | 0.654 | 0.679 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.762 | 0.451 | 0.657 | 0.532 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | GLI-lile {2.3.3.1} (TFClass) |
| TFClass ID | TFClass: 2.3.3.1.4 |
| HGNC | HGNC:29525 |
| MGI | MGI:2386723 |
| EntrezGene (human) | GeneID:148979 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:230587 (SSTAR profile) |
| UniProt ID (human) | GLIS1_HUMAN |
| UniProt ID (mouse) | GLIS1_MOUSE |
| UniProt AC (human) | Q8NBF1 (TFClass) |
| UniProt AC (mouse) | Q8K1M4 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | GLIS1.H12INVITRO.2.SM.B.pcm |
| PWM | GLIS1.H12INVITRO.2.SM.B.pwm |
| PFM | GLIS1.H12INVITRO.2.SM.B.pfm |
| Alignment | GLIS1.H12INVITRO.2.SM.B.words.tsv |
| Threshold to P-value map | GLIS1.H12INVITRO.2.SM.B.thr |
| Motif in other formats | |
| JASPAR format | GLIS1.H12INVITRO.2.SM.B_jaspar_format.txt |
| MEME format | GLIS1.H12INVITRO.2.SM.B_meme_format.meme |
| Transfac format | GLIS1.H12INVITRO.2.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2099.25 | 1581.25 | 2589.25 | 2297.25 |
| 02 | 2602.5 | 1615.5 | 1958.5 | 2390.5 |
| 03 | 1562.0 | 625.0 | 4302.0 | 2078.0 |
| 04 | 296.0 | 7363.0 | 789.0 | 119.0 |
| 05 | 2686.0 | 339.0 | 643.0 | 4899.0 |
| 06 | 2130.0 | 2639.0 | 289.0 | 3509.0 |
| 07 | 1655.0 | 4292.0 | 660.0 | 1960.0 |
| 08 | 38.0 | 92.0 | 8406.0 | 31.0 |
| 09 | 36.0 | 572.0 | 35.0 | 7924.0 |
| 10 | 252.0 | 0.0 | 8298.0 | 17.0 |
| 11 | 0.0 | 1.0 | 8493.0 | 73.0 |
| 12 | 1.0 | 0.0 | 8564.0 | 2.0 |
| 13 | 156.0 | 0.0 | 8395.0 | 16.0 |
| 14 | 2.0 | 0.0 | 8562.0 | 3.0 |
| 15 | 38.0 | 5.0 | 8496.0 | 28.0 |
| 16 | 15.0 | 414.0 | 561.0 | 7577.0 |
| 17 | 3928.0 | 2927.0 | 1577.0 | 135.0 |
| 18 | 2497.5 | 978.5 | 3388.5 | 1702.5 |
| 19 | 1752.25 | 1495.25 | 3139.25 | 2180.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.245 | 0.185 | 0.302 | 0.268 |
| 02 | 0.304 | 0.189 | 0.229 | 0.279 |
| 03 | 0.182 | 0.073 | 0.502 | 0.243 |
| 04 | 0.035 | 0.859 | 0.092 | 0.014 |
| 05 | 0.314 | 0.04 | 0.075 | 0.572 |
| 06 | 0.249 | 0.308 | 0.034 | 0.41 |
| 07 | 0.193 | 0.501 | 0.077 | 0.229 |
| 08 | 0.004 | 0.011 | 0.981 | 0.004 |
| 09 | 0.004 | 0.067 | 0.004 | 0.925 |
| 10 | 0.029 | 0.0 | 0.969 | 0.002 |
| 11 | 0.0 | 0.0 | 0.991 | 0.009 |
| 12 | 0.0 | 0.0 | 1.0 | 0.0 |
| 13 | 0.018 | 0.0 | 0.98 | 0.002 |
| 14 | 0.0 | 0.0 | 0.999 | 0.0 |
| 15 | 0.004 | 0.001 | 0.992 | 0.003 |
| 16 | 0.002 | 0.048 | 0.065 | 0.884 |
| 17 | 0.459 | 0.342 | 0.184 | 0.016 |
| 18 | 0.292 | 0.114 | 0.396 | 0.199 |
| 19 | 0.205 | 0.175 | 0.366 | 0.254 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.02 | -0.303 | 0.19 | 0.07 |
| 02 | 0.195 | -0.282 | -0.089 | 0.11 |
| 03 | -0.315 | -1.229 | 0.697 | -0.03 |
| 04 | -1.972 | 1.234 | -0.997 | -2.872 |
| 05 | 0.226 | -1.838 | -1.201 | 0.827 |
| 06 | -0.005 | 0.209 | -1.996 | 0.493 |
| 07 | -0.258 | 0.695 | -1.175 | -0.089 |
| 08 | -3.975 | -3.124 | 1.367 | -4.166 |
| 09 | -4.026 | -1.317 | -4.052 | 1.308 |
| 10 | -2.132 | -6.853 | 1.354 | -4.712 |
| 11 | -6.853 | -6.488 | 1.377 | -3.349 |
| 12 | -6.488 | -6.853 | 1.385 | -6.22 |
| 13 | -2.606 | -6.853 | 1.365 | -4.766 |
| 14 | -6.22 | -6.853 | 1.385 | -6.01 |
| 15 | -3.975 | -5.688 | 1.377 | -4.26 |
| 16 | -4.822 | -1.639 | -1.337 | 1.263 |
| 17 | 0.606 | 0.312 | -0.306 | -2.749 |
| 18 | 0.154 | -0.782 | 0.458 | -0.229 |
| 19 | -0.2 | -0.359 | 0.382 | 0.018 |
| P-value | Threshold |
|---|---|
| 0.001 | -1.96499 |
| 0.0005 | -0.13824 |
| 0.0001 | 3.67826 |