MotifGLIS1.H12INVITRO.0.P.B
Gene (human)GLIS1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Glis1
Gene synonyms (mouse)Gli5
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusSdYhSYRGGRGGYv
GC content71.97%
Information content (bits; total / per base)11.907 / 0.851
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (12) 0.868 0.92 0.743 0.838 0.795 0.833 2.381 2.577 130.436 279.456

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.956 0.94 0.876 0.866 0.753 0.766
best 0.992 0.988 0.975 0.966 0.873 0.872
Methyl HT-SELEX, 1 experiments median 0.992 0.988 0.975 0.966 0.873 0.872
best 0.992 0.988 0.975 0.966 0.873 0.872
Non-Methyl HT-SELEX, 1 experiments median 0.919 0.892 0.777 0.767 0.633 0.66
best 0.919 0.892 0.777 0.767 0.633 0.66

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.711 0.388 0.586 0.491
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.4
HGNCHGNC:29525
MGIMGI:2386723
EntrezGene (human)GeneID:148979
(SSTAR profile)
EntrezGene (mouse)GeneID:230587
(SSTAR profile)
UniProt ID (human)GLIS1_HUMAN
UniProt ID (mouse)GLIS1_MOUSE
UniProt AC (human)Q8NBF1
(TFClass)
UniProt AC (mouse)Q8K1M4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
0197.0693.0196.014.0
02213.0143.0217.0427.0
0340.0729.0111.0120.0
04175.0335.059.0431.0
058.0414.0558.020.0
0615.0593.016.0376.0
07329.04.0493.0174.0
088.02.0925.065.0
091.01.0992.06.0
10475.04.0457.064.0
119.02.0987.02.0
12114.014.0825.047.0
1314.0479.0162.0345.0
14205.0483.0182.0130.0
PFM
ACGT
010.0970.6930.1960.014
020.2130.1430.2170.427
030.040.7290.1110.12
040.1750.3350.0590.431
050.0080.4140.5580.02
060.0150.5930.0160.376
070.3290.0040.4930.174
080.0080.0020.9250.065
090.0010.0010.9920.006
100.4750.0040.4570.064
110.0090.0020.9870.002
120.1140.0140.8250.047
130.0140.4790.1620.345
140.2050.4830.1820.13
PWM
ACGT
01-0.9361.015-0.241-2.773
02-0.159-0.553-0.1410.532
03-1.7971.066-0.803-0.727
04-0.3540.291-1.4220.542
05-3.2530.5020.799-2.45
06-2.7110.86-2.6530.406
070.273-3.7830.676-0.359
08-3.253-4.2131.303-1.328
09-4.525-4.5251.373-3.484
100.639-3.7830.6-1.343
11-3.156-4.2131.368-4.213
12-0.777-2.7731.189-1.642
13-2.7730.647-0.430.32
14-0.1970.655-0.315-0.648
Standard thresholds
P-value Threshold
0.001 4.15626
0.0005 5.20586
0.0001 7.30916