GLIS1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GLIS1.H12CORE.0.P.B
Gene (human)	GLIS1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Glis1
Gene synonyms (mouse)	Gli5
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	SdYhSYRGGRGGYv
GC content	71.97%
Information content (bits; total / per base)	11.907 / 0.851
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.868	0.92	0.743	0.838	0.795	0.833	2.381	2.577	130.436	279.456

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.956	0.94	0.876	0.866	0.753	0.766
Overall, 2 experiments	best	0.992	0.988	0.975	0.966	0.873	0.872
Methyl HT-SELEX, 1 experiments	median	0.992	0.988	0.975	0.966	0.873	0.872
Methyl HT-SELEX, 1 experiments	best	0.992	0.988	0.975	0.966	0.873	0.872
Non-Methyl HT-SELEX, 1 experiments	median	0.919	0.892	0.777	0.767	0.633	0.66
Non-Methyl HT-SELEX, 1 experiments	best	0.919	0.892	0.777	0.767	0.633	0.66

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.711	0.388	0.586	0.491

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.4
HGNC	HGNC:29525
MGI	MGI:2386723
EntrezGene (human)	GeneID:148979 (SSTAR profile)
EntrezGene (mouse)	GeneID:230587 (SSTAR profile)
UniProt ID (human)	GLIS1_HUMAN
UniProt ID (mouse)	GLIS1_MOUSE
UniProt AC (human)	Q8NBF1 (TFClass)
UniProt AC (mouse)	Q8K1M4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	GLIS1.H12CORE.0.P.B.pcm
PWM	GLIS1.H12CORE.0.P.B.pwm
PFM	GLIS1.H12CORE.0.P.B.pfm
Alignment	GLIS1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	GLIS1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	GLIS1.H12CORE.0.P.B_jaspar_format.txt
MEME format	GLIS1.H12CORE.0.P.B_meme_format.meme
Transfac format	GLIS1.H12CORE.0.P.B_transfac_format.txt
Homer format	GLIS1.H12CORE.0.P.B_homer_format_0.001.txt GLIS1.H12CORE.0.P.B_homer_format_0.0005.txt GLIS1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	97.0	693.0	196.0	14.0
02	213.0	143.0	217.0	427.0
03	40.0	729.0	111.0	120.0
04	175.0	335.0	59.0	431.0
05	8.0	414.0	558.0	20.0
06	15.0	593.0	16.0	376.0
07	329.0	4.0	493.0	174.0
08	8.0	2.0	925.0	65.0
09	1.0	1.0	992.0	6.0
10	475.0	4.0	457.0	64.0
11	9.0	2.0	987.0	2.0
12	114.0	14.0	825.0	47.0
13	14.0	479.0	162.0	345.0
14	205.0	483.0	182.0	130.0

PFM

	A	C	G	T
01	0.097	0.693	0.196	0.014
02	0.213	0.143	0.217	0.427
03	0.04	0.729	0.111	0.12
04	0.175	0.335	0.059	0.431
05	0.008	0.414	0.558	0.02
06	0.015	0.593	0.016	0.376
07	0.329	0.004	0.493	0.174
08	0.008	0.002	0.925	0.065
09	0.001	0.001	0.992	0.006
10	0.475	0.004	0.457	0.064
11	0.009	0.002	0.987	0.002
12	0.114	0.014	0.825	0.047
13	0.014	0.479	0.162	0.345
14	0.205	0.483	0.182	0.13

PWM

	A	C	G	T
01	-0.936	1.015	-0.241	-2.773
02	-0.159	-0.553	-0.141	0.532
03	-1.797	1.066	-0.803	-0.727
04	-0.354	0.291	-1.422	0.542
05	-3.253	0.502	0.799	-2.45
06	-2.711	0.86	-2.653	0.406
07	0.273	-3.783	0.676	-0.359
08	-3.253	-4.213	1.303	-1.328
09	-4.525	-4.525	1.373	-3.484
10	0.639	-3.783	0.6	-1.343
11	-3.156	-4.213	1.368	-4.213
12	-0.777	-2.773	1.189	-1.642
13	-2.773	0.647	-0.43	0.32
14	-0.197	0.655	-0.315	-0.648

Standard thresholds

P-value	Threshold
0.001	4.15626
0.0005	5.20586
0.0001	7.30916