MotifGLI3.H12INVITRO.0.PS.A
Gene (human)GLI3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gli3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusSdhSGTGGGTGGTCbn
GC content64.66%
Information content (bits; total / per base)20.579 / 1.286
Data sourcesChIP-Seq + HT-SELEX
Aligned words9711

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (8) 0.757 0.803 0.688 0.744 0.736 0.797 3.107 3.476 36.989 69.638

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.884 0.904 0.795 0.832
best 1.0 1.0 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 1 experiments median 0.996 0.995 0.769 0.808 0.591 0.664
best 0.996 0.995 0.769 0.808 0.591 0.664
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 0.999 0.999 0.999
best 1.0 1.0 1.0 0.999 0.999 0.999

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.586 0.226 0.333 0.15
batch 2 0.811 0.451 0.836 0.595
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.3
HGNCHGNC:4319
MGIMGI:95729
EntrezGene (human)GeneID:2737
(SSTAR profile)
EntrezGene (mouse)GeneID:14634
(SSTAR profile)
UniProt ID (human)GLI3_HUMAN
UniProt ID (mouse)GLI3_MOUSE
UniProt AC (human)P10071
(TFClass)
UniProt AC (mouse)Q61602
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01892.56908.51290.5619.5
021966.251106.254050.252588.25
033355.01333.01161.03862.0
04387.06050.02020.01254.0
05188.0220.08805.0498.0
066.085.011.09609.0
0718.03.09677.013.0
080.02.09554.0155.0
090.00.09710.01.0
105.00.02.09704.0
110.00.09711.00.0
122.03.09706.00.0
133.0137.0396.09175.0
1495.09566.033.017.0
15357.52978.51852.54522.5
162385.01841.02251.03234.0
PFM
ACGT
010.0920.7110.1330.064
020.2020.1140.4170.267
030.3450.1370.120.398
040.040.6230.2080.129
050.0190.0230.9070.051
060.0010.0090.0010.989
070.0020.00.9960.001
080.00.00.9840.016
090.00.01.00.0
100.0010.00.00.999
110.00.01.00.0
120.00.00.9990.0
130.00.0140.0410.945
140.010.9850.0030.002
150.0370.3070.1910.466
160.2460.190.2320.333
PWM
ACGT
01-0.9991.045-0.631-1.363
02-0.211-0.7850.5110.064
030.323-0.599-0.7370.464
04-1.8310.913-0.184-0.66
05-2.547-2.3921.288-1.58
06-5.68-3.326-5.2081.375
07-4.785-6.1291.382-5.068
08-6.965-6.3381.369-2.738
09-6.965-6.9651.385-6.603
10-5.808-6.965-6.3381.385
11-6.965-6.9651.386-6.965
12-6.338-6.1291.385-6.965
13-6.129-2.859-1.8081.329
14-3.2181.371-4.232-4.836
15-1.910.204-0.270.622
16-0.018-0.276-0.0760.287
Standard thresholds
P-value Threshold
0.001 -4.42794
0.0005 -2.35624
0.0001 2.03231