GFI1B.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GFI1B.H12INVIVO.0.PSM.A
Gene (human)	GFI1B (GeneCards)
Gene synonyms (human)
Gene (mouse)	Gfi1b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	dRYWSWGATTK
GC content	39.14%
Information content (bits; total / per base)	11.233 / 1.021
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	1007

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (41)	0.867	0.915	0.776	0.846	0.864	0.916	3.034	3.589	196.585	340.208
Mouse	5 (27)	0.823	0.92	0.709	0.841	0.806	0.903	2.656	3.37	163.06	343.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.974	0.967	0.801	0.816	0.637	0.683
Overall, 2 experiments	best	0.987	0.983	0.844	0.854	0.66	0.707
Methyl HT-SELEX, 1 experiments	median	0.961	0.952	0.758	0.779	0.614	0.659
Methyl HT-SELEX, 1 experiments	best	0.961	0.952	0.758	0.779	0.614	0.659
Non-Methyl HT-SELEX, 1 experiments	median	0.987	0.983	0.844	0.854	0.66	0.707
Non-Methyl HT-SELEX, 1 experiments	best	0.987	0.983	0.844	0.854	0.66	0.707

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GFI1 {2.3.3.21} (TFClass)
TFClass ID	TFClass: 2.3.3.21.2
HGNC	HGNC:4238
MGI	MGI:1276578
EntrezGene (human)	GeneID:8328 (SSTAR profile)
EntrezGene (mouse)	GeneID:14582 (SSTAR profile)
UniProt ID (human)	GFI1B_HUMAN
UniProt ID (mouse)	GFI1B_MOUSE
UniProt AC (human)	Q5VTD9 (TFClass)
UniProt AC (mouse)	O70237 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 5 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	GFI1B.H12INVIVO.0.PSM.A.pcm
PWM	GFI1B.H12INVIVO.0.PSM.A.pwm
PFM	GFI1B.H12INVIVO.0.PSM.A.pfm
Alignment	GFI1B.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	GFI1B.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	GFI1B.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	GFI1B.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	GFI1B.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	GFI1B.H12INVIVO.0.PSM.A_homer_format_0.001.txt GFI1B.H12INVIVO.0.PSM.A_homer_format_0.0005.txt GFI1B.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	290.0	95.0	307.0	315.0
02	181.0	77.0	604.0	145.0
03	77.0	781.0	55.0	94.0
04	368.0	133.0	6.0	500.0
05	16.0	405.0	476.0	110.0
06	383.0	1.0	20.0	603.0
07	0.0	0.0	1005.0	2.0
08	901.0	33.0	72.0	1.0
09	4.0	7.0	2.0	994.0
10	2.0	2.0	0.0	1003.0
11	65.0	119.0	135.0	688.0

PFM

	A	C	G	T
01	0.288	0.094	0.305	0.313
02	0.18	0.076	0.6	0.144
03	0.076	0.776	0.055	0.093
04	0.365	0.132	0.006	0.497
05	0.016	0.402	0.473	0.109
06	0.38	0.001	0.02	0.599
07	0.0	0.0	0.998	0.002
08	0.895	0.033	0.071	0.001
09	0.004	0.007	0.002	0.987
10	0.002	0.002	0.0	0.996
11	0.065	0.118	0.134	0.683

PWM

	A	C	G	T
01	0.141	-0.963	0.197	0.223
02	-0.327	-1.169	0.871	-0.547
03	-1.169	1.128	-1.497	-0.974
04	0.377	-0.632	-3.49	0.683
05	-2.66	0.473	0.634	-0.819
06	0.417	-4.531	-2.457	0.87
07	-4.988	-4.988	1.379	-4.219
08	1.27	-1.988	-1.235	-4.531
09	-3.79	-3.369	-4.219	1.368
10	-4.219	-4.219	-4.988	1.377
11	-1.335	-0.742	-0.617	1.001

Standard thresholds

P-value	Threshold
0.001	4.41836
0.0005	5.48224
0.0001	7.46035