| Motif | GFI1B.H12CORE.1.S.C |
| Gene (human) | GFI1B (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Gfi1b |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | GFI1B.H12CORE.1.S.C |
| Gene (human) | GFI1B (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Gfi1b |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 21 |
| Consensus | dWdKRvvndGCMGTGATTTvh |
| GC content | 43.13% |
| Information content (bits; total / per base) | 19.509 / 0.929 |
| Data sources | HT-SELEX |
| Aligned words | 8816 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (41) | 0.836 | 0.871 | 0.722 | 0.788 | 0.817 | 0.861 | 2.689 | 3.254 | 98.18 | 220.921 |
| Mouse | 5 (27) | 0.789 | 0.891 | 0.685 | 0.804 | 0.769 | 0.869 | 2.424 | 3.073 | 90.071 | 206.569 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.967 | 0.967 | 0.774 | 0.8 | 0.625 | 0.673 |
| best | 0.998 | 0.997 | 0.837 | 0.856 | 0.662 | 0.71 | |
| Methyl HT-SELEX, 1 experiments | median | 0.937 | 0.938 | 0.711 | 0.745 | 0.589 | 0.636 |
| best | 0.937 | 0.938 | 0.711 | 0.745 | 0.589 | 0.636 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.998 | 0.997 | 0.837 | 0.856 | 0.662 | 0.71 |
| best | 0.998 | 0.997 | 0.837 | 0.856 | 0.662 | 0.71 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | GFI1 {2.3.3.21} (TFClass) |
| TFClass ID | TFClass: 2.3.3.21.2 |
| HGNC | HGNC:4238 |
| MGI | MGI:1276578 |
| EntrezGene (human) | GeneID:8328 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:14582 (SSTAR profile) |
| UniProt ID (human) | GFI1B_HUMAN |
| UniProt ID (mouse) | GFI1B_MOUSE |
| UniProt AC (human) | Q5VTD9 (TFClass) |
| UniProt AC (mouse) | O70237 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 5 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | GFI1B.H12CORE.1.S.C.pcm |
| PWM | GFI1B.H12CORE.1.S.C.pwm |
| PFM | GFI1B.H12CORE.1.S.C.pfm |
| Alignment | GFI1B.H12CORE.1.S.C.words.tsv |
| Threshold to P-value map | GFI1B.H12CORE.1.S.C.thr |
| Motif in other formats | |
| JASPAR format | GFI1B.H12CORE.1.S.C_jaspar_format.txt |
| MEME format | GFI1B.H12CORE.1.S.C_meme_format.meme |
| Transfac format | GFI1B.H12CORE.1.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1779.25 | 1687.25 | 3651.25 | 1698.25 |
| 02 | 6340.5 | 446.5 | 999.5 | 1029.5 |
| 03 | 1492.0 | 790.0 | 5053.0 | 1481.0 |
| 04 | 926.0 | 619.0 | 1233.0 | 6038.0 |
| 05 | 1122.0 | 1050.0 | 5879.0 | 765.0 |
| 06 | 3515.0 | 2614.0 | 1957.0 | 730.0 |
| 07 | 3062.0 | 1515.0 | 2891.0 | 1348.0 |
| 08 | 2039.0 | 1789.0 | 2957.0 | 2031.0 |
| 09 | 1479.0 | 1021.0 | 1107.0 | 5209.0 |
| 10 | 819.0 | 92.0 | 7738.0 | 167.0 |
| 11 | 137.0 | 8364.0 | 67.0 | 248.0 |
| 12 | 6412.0 | 1309.0 | 26.0 | 1069.0 |
| 13 | 6.0 | 2243.0 | 6496.0 | 71.0 |
| 14 | 78.0 | 3.0 | 4.0 | 8731.0 |
| 15 | 0.0 | 0.0 | 8816.0 | 0.0 |
| 16 | 8816.0 | 0.0 | 0.0 | 0.0 |
| 17 | 0.0 | 2.0 | 2.0 | 8812.0 |
| 18 | 2.0 | 0.0 | 3.0 | 8811.0 |
| 19 | 98.0 | 102.0 | 1053.0 | 7563.0 |
| 20 | 4345.75 | 1506.75 | 1684.75 | 1278.75 |
| 21 | 1868.75 | 1709.75 | 1363.75 | 3873.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.202 | 0.191 | 0.414 | 0.193 |
| 02 | 0.719 | 0.051 | 0.113 | 0.117 |
| 03 | 0.169 | 0.09 | 0.573 | 0.168 |
| 04 | 0.105 | 0.07 | 0.14 | 0.685 |
| 05 | 0.127 | 0.119 | 0.667 | 0.087 |
| 06 | 0.399 | 0.297 | 0.222 | 0.083 |
| 07 | 0.347 | 0.172 | 0.328 | 0.153 |
| 08 | 0.231 | 0.203 | 0.335 | 0.23 |
| 09 | 0.168 | 0.116 | 0.126 | 0.591 |
| 10 | 0.093 | 0.01 | 0.878 | 0.019 |
| 11 | 0.016 | 0.949 | 0.008 | 0.028 |
| 12 | 0.727 | 0.148 | 0.003 | 0.121 |
| 13 | 0.001 | 0.254 | 0.737 | 0.008 |
| 14 | 0.009 | 0.0 | 0.0 | 0.99 |
| 15 | 0.0 | 0.0 | 1.0 | 0.0 |
| 16 | 1.0 | 0.0 | 0.0 | 0.0 |
| 17 | 0.0 | 0.0 | 0.0 | 1.0 |
| 18 | 0.0 | 0.0 | 0.0 | 0.999 |
| 19 | 0.011 | 0.012 | 0.119 | 0.858 |
| 20 | 0.493 | 0.171 | 0.191 | 0.145 |
| 21 | 0.212 | 0.194 | 0.155 | 0.439 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.214 | -0.267 | 0.504 | -0.26 |
| 02 | 1.056 | -1.593 | -0.79 | -0.76 |
| 03 | -0.39 | -1.024 | 0.829 | -0.397 |
| 04 | -0.866 | -1.267 | -0.58 | 1.007 |
| 05 | -0.674 | -0.74 | 0.98 | -1.056 |
| 06 | 0.466 | 0.17 | -0.119 | -1.103 |
| 07 | 0.329 | -0.374 | 0.271 | -0.491 |
| 08 | -0.078 | -0.208 | 0.294 | -0.082 |
| 09 | -0.398 | -0.768 | -0.688 | 0.86 |
| 10 | -0.988 | -3.153 | 1.255 | -2.568 |
| 11 | -2.763 | 1.333 | -3.461 | -2.177 |
| 12 | 1.067 | -0.52 | -4.357 | -0.722 |
| 13 | -5.586 | 0.018 | 1.08 | -3.405 |
| 14 | -3.314 | -6.037 | -5.863 | 1.376 |
| 15 | -6.879 | -6.879 | 1.386 | -6.879 |
| 16 | 1.386 | -6.879 | -6.879 | -6.879 |
| 17 | -6.879 | -6.247 | -6.247 | 1.385 |
| 18 | -6.247 | -6.879 | -6.037 | 1.385 |
| 19 | -3.091 | -3.052 | -0.738 | 1.232 |
| 20 | 0.678 | -0.38 | -0.268 | -0.544 |
| 21 | -0.165 | -0.254 | -0.479 | 0.564 |
| P-value | Threshold |
|---|---|
| 0.001 | -1.79499 |
| 0.0005 | 0.08011 |
| 0.0001 | 3.98221 |