GFI1B.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GFI1B.H12CORE.0.PSM.A
Gene (human)	GFI1B (GeneCards)
Gene synonyms (human)
Gene (mouse)	Gfi1b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	dRCWSWGATTK
GC content	39.61%
Information content (bits; total / per base)	11.733 / 1.067
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	6 (41)	0.867	0.914	0.766	0.836	0.866	0.915	3.019	3.595	200.602	338.469
Mouse	5 (27)	0.827	0.924	0.724	0.85	0.81	0.907	2.703	3.441	165.201	340.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.978	0.972	0.805	0.821	0.64	0.686
Overall, 2 experiments	best	0.99	0.986	0.846	0.858	0.662	0.71
Methyl HT-SELEX, 1 experiments	median	0.966	0.958	0.764	0.785	0.618	0.663
Methyl HT-SELEX, 1 experiments	best	0.966	0.958	0.764	0.785	0.618	0.663
Non-Methyl HT-SELEX, 1 experiments	median	0.99	0.986	0.846	0.858	0.662	0.71
Non-Methyl HT-SELEX, 1 experiments	best	0.99	0.986	0.846	0.858	0.662	0.71

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GFI1 {2.3.3.21} (TFClass)
TFClass ID	TFClass: 2.3.3.21.2
HGNC	HGNC:4238
MGI	MGI:1276578
EntrezGene (human)	GeneID:8328 (SSTAR profile)
EntrezGene (mouse)	GeneID:14582 (SSTAR profile)
UniProt ID (human)	GFI1B_HUMAN
UniProt ID (mouse)	GFI1B_MOUSE
UniProt AC (human)	Q5VTD9 (TFClass)
UniProt AC (mouse)	O70237 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	6 human, 5 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	GFI1B.H12CORE.0.PSM.A.pcm
PWM	GFI1B.H12CORE.0.PSM.A.pwm
PFM	GFI1B.H12CORE.0.PSM.A.pfm
Alignment	GFI1B.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	GFI1B.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	GFI1B.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	GFI1B.H12CORE.0.PSM.A_meme_format.meme
Transfac format	GFI1B.H12CORE.0.PSM.A_transfac_format.txt
Homer format	GFI1B.H12CORE.0.PSM.A_homer_format_0.001.txt GFI1B.H12CORE.0.PSM.A_homer_format_0.0005.txt GFI1B.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	302.0	115.0	254.0	329.0
02	180.0	65.0	648.0	107.0
03	55.0	810.0	37.0	98.0
04	351.0	124.0	12.0	513.0
05	10.0	333.0	583.0	74.0
06	427.0	1.0	9.0	563.0
07	0.0	3.0	993.0	4.0
08	915.0	16.0	67.0	2.0
09	0.0	6.0	6.0	988.0
10	3.0	2.0	1.0	994.0
11	43.0	96.0	176.0	685.0

PFM

	A	C	G	T
01	0.302	0.115	0.254	0.329
02	0.18	0.065	0.648	0.107
03	0.055	0.81	0.037	0.098
04	0.351	0.124	0.012	0.513
05	0.01	0.333	0.583	0.074
06	0.427	0.001	0.009	0.563
07	0.0	0.003	0.993	0.004
08	0.915	0.016	0.067	0.002
09	0.0	0.006	0.006	0.988
10	0.003	0.002	0.001	0.994
11	0.043	0.096	0.176	0.685

PWM

	A	C	G	T
01	0.188	-0.769	0.016	0.273
02	-0.326	-1.328	0.948	-0.84
03	-1.49	1.171	-1.872	-0.926
04	0.337	-0.694	-2.909	0.715
05	-3.066	0.285	0.843	-1.201
06	0.532	-4.525	-3.156	0.808
07	-4.982	-3.975	1.374	-3.783
08	1.292	-2.653	-1.298	-4.213
09	-4.982	-3.484	-3.484	1.369
10	-3.975	-4.213	-4.525	1.375
11	-1.728	-0.946	-0.348	1.004

Standard thresholds

P-value	Threshold
0.001	4.15617
0.0005	5.270345
0.0001	7.41549