MotifGFI1.H12INVITRO.0.PSM.A
Gene (human)GFI1
(GeneCards)
Gene synonyms (human)ZNF163
Gene (mouse)Gfi1
Gene synonyms (mouse)Gfi-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusdvnnndGCMGTGATTKvn
GC content46.27%
Information content (bits; total / per base)15.901 / 0.883
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9991

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (15) 0.818 0.89 0.745 0.825 0.813 0.877 3.125 3.457 118.886 255.886
Mouse 5 (31) 0.75 0.889 0.627 0.807 0.761 0.87 2.453 3.167 81.301 246.076

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.999 0.999 0.999 0.998 0.994 0.992
best 0.999 0.999 0.999 0.998 0.995 0.993
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.993 0.991
best 0.999 0.999 0.999 0.998 0.993 0.991
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.995 0.993
best 0.999 0.999 0.999 0.998 0.995 0.993

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.733 0.562 0.762 0.59
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGFI1 {2.3.3.21} (TFClass)
TFClass IDTFClass: 2.3.3.21.1
HGNCHGNC:4237
MGIMGI:103170
EntrezGene (human)GeneID:2672
(SSTAR profile)
EntrezGene (mouse)GeneID:14581
(SSTAR profile)
UniProt ID (human)GFI1_HUMAN
UniProt ID (mouse)GFI1_MOUSE
UniProt AC (human)Q99684
(TFClass)
UniProt AC (mouse)P70338
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 5 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011463.01024.02349.05155.0
021689.01629.05367.01306.0
033205.02746.02860.01180.0
042700.01831.03667.01793.0
051658.02042.03913.02378.0
061666.01401.02318.04606.0
071254.0214.08121.0402.0
08283.08963.0271.0474.0
095971.02450.062.01508.0
105.01415.08471.0100.0
11178.08.028.09777.0
1221.08.09960.02.0
139899.065.015.012.0
1434.026.056.09875.0
1532.027.045.09887.0
16231.0219.02116.07425.0
173911.752126.752759.751192.75
182556.52095.52539.52799.5
PFM
ACGT
010.1460.1020.2350.516
020.1690.1630.5370.131
030.3210.2750.2860.118
040.270.1830.3670.179
050.1660.2040.3920.238
060.1670.140.2320.461
070.1260.0210.8130.04
080.0280.8970.0270.047
090.5980.2450.0060.151
100.0010.1420.8480.01
110.0180.0010.0030.979
120.0020.0010.9970.0
130.9910.0070.0020.001
140.0030.0030.0060.988
150.0030.0030.0050.99
160.0230.0220.2120.743
170.3920.2130.2760.119
180.2560.210.2540.28
PWM
ACGT
01-0.534-0.89-0.0610.724
02-0.391-0.4270.764-0.648
030.2490.0950.135-0.749
040.078-0.310.384-0.331
05-0.409-0.2010.449-0.049
06-0.405-0.577-0.0750.612
07-0.688-2.4471.178-1.822
08-2.1711.277-2.213-1.658
090.871-0.019-3.66-0.504
10-5.836-0.5681.221-3.196
11-2.629-5.492-4.4131.364
12-4.676-5.4921.382-6.365
131.376-3.615-4.973-5.164
14-4.232-4.481-3.7581.374
15-4.289-4.446-3.9681.375
16-2.372-2.425-0.1661.089
170.448-0.1610.1-0.738
180.023-0.1750.0170.114
Standard thresholds
P-value Threshold
0.001 1.59821
0.0005 3.03951
0.0001 6.03646