MotifGCR.H12INVITRO.1.S.B
Gene (human)NR3C1
(GeneCards)
Gene synonyms (human)GRL
Gene (mouse)Nr3c1
Gene synonyms (mouse)Grl, Grl1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length9
ConsensusnvYGTWCbn
GC content46.28%
Information content (bits; total / per base)6.657 / 0.74
Data sourcesHT-SELEX
Aligned words9618

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 82 (479) 0.782 0.905 0.628 0.81 0.715 0.797 1.758 2.04 73.114 233.77
Mouse 93 (512) 0.741 0.836 0.578 0.713 0.703 0.797 1.704 2.048 68.594 233.252

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.759 0.727 0.654 0.641 0.588 0.589
best 0.822 0.799 0.689 0.683 0.606 0.614

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.563 15.76 0.133 0.055
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familySteroid hormone receptors {2.1.1} (TFClass)
TF subfamilyGR-like (NR3C) {2.1.1.1} (TFClass)
TFClass IDTFClass: 2.1.1.1.1
HGNCHGNC:7978
MGIMGI:95824
EntrezGene (human)GeneID:2908
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)GCR_HUMAN
UniProt ID (mouse)GCR_MOUSE
UniProt AC (human)P04150
(TFClass)
UniProt AC (mouse)P06537
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 82 human, 93 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
012799.752608.751792.752416.75
024215.251514.252844.251044.25
03830.01453.0247.07088.0
041.078.09441.098.0
05104.0137.00.09377.0
063245.0865.0547.04961.0
07252.08423.057.0886.0
08955.03698.01550.03415.0
091904.752691.752114.752906.75
PFM
ACGT
010.2910.2710.1860.251
020.4380.1570.2960.109
030.0860.1510.0260.737
040.00.0080.9820.01
050.0110.0140.00.975
060.3370.090.0570.516
070.0260.8760.0060.092
080.0990.3840.1610.355
090.1980.280.220.302
PWM
ACGT
010.1520.081-0.2930.005
020.561-0.4620.168-0.833
03-1.062-0.503-2.2671.08
04-6.594-3.41.367-3.178
05-3.12-2.849-6.9561.36
060.3-1.021-1.4770.724
07-2.2481.253-3.704-0.997
08-0.9220.43-0.4390.351
09-0.2330.113-0.1280.19
Standard thresholds
P-value Threshold
0.001 5.284805
0.0005 5.832095
0.0001 6.616505