| Motif | GCR.H12CORE.1.S.B |
| Gene (human) | NR3C1 (GeneCards) |
| Gene synonyms (human) | GRL |
| Gene (mouse) | Nr3c1 |
| Gene synonyms (mouse) | Grl, Grl1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | GCR.H12CORE.1.S.B |
| Gene (human) | NR3C1 (GeneCards) |
| Gene synonyms (human) | GRL |
| Gene (mouse) | Nr3c1 |
| Gene synonyms (mouse) | Grl, Grl1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 9 |
| Consensus | nvYGTWCbn |
| GC content | 46.28% |
| Information content (bits; total / per base) | 6.657 / 0.74 |
| Data sources | HT-SELEX |
| Aligned words | 9618 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 82 (479) | 0.782 | 0.905 | 0.628 | 0.81 | 0.715 | 0.797 | 1.758 | 2.04 | 73.114 | 233.77 |
| Mouse | 93 (512) | 0.741 | 0.836 | 0.578 | 0.713 | 0.703 | 0.797 | 1.704 | 2.048 | 68.594 | 233.252 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.759 | 0.727 | 0.654 | 0.641 | 0.588 | 0.589 |
| best | 0.822 | 0.799 | 0.689 | 0.683 | 0.606 | 0.614 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.563 | 15.76 | 0.133 | 0.055 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Steroid hormone receptors {2.1.1} (TFClass) |
| TF subfamily | GR-like (NR3C) {2.1.1.1} (TFClass) |
| TFClass ID | TFClass: 2.1.1.1.1 |
| HGNC | HGNC:7978 |
| MGI | MGI:95824 |
| EntrezGene (human) | GeneID:2908 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | GCR_HUMAN |
| UniProt ID (mouse) | GCR_MOUSE |
| UniProt AC (human) | P04150 (TFClass) |
| UniProt AC (mouse) | P06537 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 82 human, 93 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | GCR.H12CORE.1.S.B.pcm |
| PWM | GCR.H12CORE.1.S.B.pwm |
| PFM | GCR.H12CORE.1.S.B.pfm |
| Alignment | GCR.H12CORE.1.S.B.words.tsv |
| Threshold to P-value map | GCR.H12CORE.1.S.B.thr |
| Motif in other formats | |
| JASPAR format | GCR.H12CORE.1.S.B_jaspar_format.txt |
| MEME format | GCR.H12CORE.1.S.B_meme_format.meme |
| Transfac format | GCR.H12CORE.1.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2799.75 | 2608.75 | 1792.75 | 2416.75 |
| 02 | 4215.25 | 1514.25 | 2844.25 | 1044.25 |
| 03 | 830.0 | 1453.0 | 247.0 | 7088.0 |
| 04 | 1.0 | 78.0 | 9441.0 | 98.0 |
| 05 | 104.0 | 137.0 | 0.0 | 9377.0 |
| 06 | 3245.0 | 865.0 | 547.0 | 4961.0 |
| 07 | 252.0 | 8423.0 | 57.0 | 886.0 |
| 08 | 955.0 | 3698.0 | 1550.0 | 3415.0 |
| 09 | 1904.75 | 2691.75 | 2114.75 | 2906.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.291 | 0.271 | 0.186 | 0.251 |
| 02 | 0.438 | 0.157 | 0.296 | 0.109 |
| 03 | 0.086 | 0.151 | 0.026 | 0.737 |
| 04 | 0.0 | 0.008 | 0.982 | 0.01 |
| 05 | 0.011 | 0.014 | 0.0 | 0.975 |
| 06 | 0.337 | 0.09 | 0.057 | 0.516 |
| 07 | 0.026 | 0.876 | 0.006 | 0.092 |
| 08 | 0.099 | 0.384 | 0.161 | 0.355 |
| 09 | 0.198 | 0.28 | 0.22 | 0.302 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.152 | 0.081 | -0.293 | 0.005 |
| 02 | 0.561 | -0.462 | 0.168 | -0.833 |
| 03 | -1.062 | -0.503 | -2.267 | 1.08 |
| 04 | -6.594 | -3.4 | 1.367 | -3.178 |
| 05 | -3.12 | -2.849 | -6.956 | 1.36 |
| 06 | 0.3 | -1.021 | -1.477 | 0.724 |
| 07 | -2.248 | 1.253 | -3.704 | -0.997 |
| 08 | -0.922 | 0.43 | -0.439 | 0.351 |
| 09 | -0.233 | 0.113 | -0.128 | 0.19 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.284805 |
| 0.0005 | 5.832095 |
| 0.0001 | 6.616505 |