| Motif | GCM2.H12RSNP.0.SM.B |
| Gene (human) | GCM2 (GeneCards) |
| Gene synonyms (human) | GCMB |
| Gene (mouse) | Gcm2 |
| Gene synonyms (mouse) | Gcmb |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | GCM2.H12RSNP.0.SM.B |
| Gene (human) | GCM2 (GeneCards) |
| Gene synonyms (human) | GCMB |
| Gene (mouse) | Gcm2 |
| Gene synonyms (mouse) | Gcmb |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | nRCCCGCATn |
| GC content | 62.55% |
| Information content (bits; total / per base) | 13.181 / 1.318 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 6405 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.97 | 0.956 | 0.879 | 0.861 | 0.789 | 0.777 |
| best | 0.992 | 0.987 | 0.987 | 0.979 | 0.959 | 0.948 | |
| Methyl HT-SELEX, 1 experiments | median | 0.954 | 0.933 | 0.878 | 0.849 | 0.858 | 0.811 |
| best | 0.954 | 0.933 | 0.878 | 0.849 | 0.858 | 0.811 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.986 | 0.979 | 0.88 | 0.873 | 0.72 | 0.742 |
| best | 0.992 | 0.987 | 0.987 | 0.979 | 0.959 | 0.948 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.918 | 0.742 | 0.894 | 0.558 |
| batch 2 | 0.815 | 0.614 | 0.798 | 0.539 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | GCM domain factors {7.2} (TFClass) |
| TF family | GCM {7.2.1} (TFClass) |
| TF subfamily | {7.2.1.0} (TFClass) |
| TFClass ID | TFClass: 7.2.1.0.2 |
| HGNC | HGNC:4198 |
| MGI | MGI:1861438 |
| EntrezGene (human) | GeneID:9247 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:107889 (SSTAR profile) |
| UniProt ID (human) | GCM2_HUMAN |
| UniProt ID (mouse) | GCM2_MOUSE |
| UniProt AC (human) | O75603 (TFClass) |
| UniProt AC (mouse) | O09102 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | GCM2.H12RSNP.0.SM.B.pcm |
| PWM | GCM2.H12RSNP.0.SM.B.pwm |
| PFM | GCM2.H12RSNP.0.SM.B.pfm |
| Alignment | GCM2.H12RSNP.0.SM.B.words.tsv |
| Threshold to P-value map | GCM2.H12RSNP.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | GCM2.H12RSNP.0.SM.B_jaspar_format.txt |
| MEME format | GCM2.H12RSNP.0.SM.B_meme_format.meme |
| Transfac format | GCM2.H12RSNP.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1659.75 | 1849.75 | 948.75 | 1946.75 |
| 02 | 4300.25 | 367.25 | 1226.25 | 511.25 |
| 03 | 0.0 | 6405.0 | 0.0 | 0.0 |
| 04 | 0.0 | 6405.0 | 0.0 | 0.0 |
| 05 | 0.0 | 6405.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 6405.0 | 0.0 |
| 07 | 0.0 | 5662.0 | 0.0 | 743.0 |
| 08 | 6405.0 | 0.0 | 0.0 | 0.0 |
| 09 | 187.0 | 795.0 | 300.0 | 5123.0 |
| 10 | 1781.75 | 1690.75 | 1604.75 | 1327.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.259 | 0.289 | 0.148 | 0.304 |
| 02 | 0.671 | 0.057 | 0.191 | 0.08 |
| 03 | 0.0 | 1.0 | 0.0 | 0.0 |
| 04 | 0.0 | 1.0 | 0.0 | 0.0 |
| 05 | 0.0 | 1.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 0.884 | 0.0 | 0.116 |
| 08 | 1.0 | 0.0 | 0.0 | 0.0 |
| 09 | 0.029 | 0.124 | 0.047 | 0.8 |
| 10 | 0.278 | 0.264 | 0.251 | 0.207 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.036 | 0.144 | -0.522 | 0.195 |
| 02 | 0.987 | -1.468 | -0.266 | -1.139 |
| 03 | -6.595 | 1.385 | -6.595 | -6.595 |
| 04 | -6.595 | 1.385 | -6.595 | -6.595 |
| 05 | -6.595 | 1.385 | -6.595 | -6.595 |
| 06 | -6.595 | -6.595 | 1.385 | -6.595 |
| 07 | -6.595 | 1.262 | -6.595 | -0.766 |
| 08 | 1.385 | -6.595 | -6.595 | -6.595 |
| 09 | -2.137 | -0.699 | -1.669 | 1.162 |
| 10 | 0.107 | 0.054 | 0.002 | -0.187 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.720905 |
| 0.0005 | 2.616335 |
| 0.0001 | 7.470405 |