MotifGCM2.H12INVITRO.0.SM.B
Gene (human)GCM2
(GeneCards)
Gene synonyms (human)GCMB
Gene (mouse)Gcm2
Gene synonyms (mouse)Gcmb
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnRCCCGCATn
GC content62.55%
Information content (bits; total / per base)13.181 / 1.318
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6405

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.97 0.956 0.879 0.861 0.789 0.777
best 0.992 0.987 0.987 0.979 0.959 0.948
Methyl HT-SELEX, 1 experiments median 0.954 0.933 0.878 0.849 0.858 0.811
best 0.954 0.933 0.878 0.849 0.858 0.811
Non-Methyl HT-SELEX, 3 experiments median 0.986 0.979 0.88 0.873 0.72 0.742
best 0.992 0.987 0.987 0.979 0.959 0.948

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.918 0.742 0.894 0.558
batch 2 0.815 0.614 0.798 0.539
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classGCM domain factors {7.2} (TFClass)
TF familyGCM {7.2.1} (TFClass)
TF subfamily {7.2.1.0} (TFClass)
TFClass IDTFClass: 7.2.1.0.2
HGNCHGNC:4198
MGIMGI:1861438
EntrezGene (human)GeneID:9247
(SSTAR profile)
EntrezGene (mouse)GeneID:107889
(SSTAR profile)
UniProt ID (human)GCM2_HUMAN
UniProt ID (mouse)GCM2_MOUSE
UniProt AC (human)O75603
(TFClass)
UniProt AC (mouse)O09102
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011659.751849.75948.751946.75
024300.25367.251226.25511.25
030.06405.00.00.0
040.06405.00.00.0
050.06405.00.00.0
060.00.06405.00.0
070.05662.00.0743.0
086405.00.00.00.0
09187.0795.0300.05123.0
101781.751690.751604.751327.75
PFM
ACGT
010.2590.2890.1480.304
020.6710.0570.1910.08
030.01.00.00.0
040.01.00.00.0
050.01.00.00.0
060.00.01.00.0
070.00.8840.00.116
081.00.00.00.0
090.0290.1240.0470.8
100.2780.2640.2510.207
PWM
ACGT
010.0360.144-0.5220.195
020.987-1.468-0.266-1.139
03-6.5951.385-6.595-6.595
04-6.5951.385-6.595-6.595
05-6.5951.385-6.595-6.595
06-6.595-6.5951.385-6.595
07-6.5951.262-6.595-0.766
081.385-6.595-6.595-6.595
09-2.137-0.699-1.6691.162
100.1070.0540.002-0.187
Standard thresholds
P-value Threshold
0.001 0.720905
0.0005 2.616335
0.0001 7.470405