MotifGBX2.H12INVIVO.1.S.D
Gene (human)GBX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gbx2
Gene synonyms (mouse)Mmoxa, Stra7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length20
ConsensusnvSTAATTASbvnhWWWWdn
GC content31.23%
Information content (bits; total / per base)15.455 / 0.773
Data sourcesHT-SELEX
Aligned words9258

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.907 0.886 0.766 0.761 0.642 0.661
best 0.997 0.996 0.981 0.977 0.96 0.938
Methyl HT-SELEX, 2 experiments median 0.962 0.945 0.902 0.886 0.817 0.814
best 0.983 0.971 0.973 0.957 0.949 0.929
Non-Methyl HT-SELEX, 8 experiments median 0.79 0.767 0.656 0.657 0.579 0.594
best 0.997 0.996 0.981 0.977 0.96 0.938

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.902 0.147 0.901 0.491
batch 2 0.809 0.726 0.786 0.532
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyGBX {3.1.1.11} (TFClass)
TFClass IDTFClass: 3.1.1.11.2
HGNCHGNC:4186
MGIMGI:95668
EntrezGene (human)GeneID:2637
(SSTAR profile)
EntrezGene (mouse)GeneID:14472
(SSTAR profile)
UniProt ID (human)GBX2_HUMAN
UniProt ID (mouse)GBX2_MOUSE
UniProt AC (human)P52951
(TFClass)
UniProt AC (mouse)P48031
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 8
Methyl-HT-SELEX 2
PCM
ACGT
012393.53475.51818.51570.5
023244.52806.52374.5832.5
03314.06459.01580.0905.0
040.01299.00.07959.0
059258.00.00.00.0
069258.00.00.00.0
070.00.00.09258.0
080.00.00.09258.0
096530.00.02728.00.0
10892.02297.05873.0196.0
11776.03191.01580.03711.0
121643.03582.02508.01525.0
133033.02789.01241.02195.0
143483.01677.0833.03265.0
154291.0952.0321.03694.0
164997.0378.092.03791.0
174444.0122.0182.04510.0
183154.0306.0666.05132.0
192712.25610.251993.253942.25
202301.751351.752732.752871.75
PFM
ACGT
010.2590.3750.1960.17
020.350.3030.2560.09
030.0340.6980.1710.098
040.00.140.00.86
051.00.00.00.0
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
090.7050.00.2950.0
100.0960.2480.6340.021
110.0840.3450.1710.401
120.1770.3870.2710.165
130.3280.3010.1340.237
140.3760.1810.090.353
150.4630.1030.0350.399
160.540.0410.010.409
170.480.0130.020.487
180.3410.0330.0720.554
190.2930.0660.2150.426
200.2490.1460.2950.31
PWM
ACGT
010.0340.406-0.241-0.387
020.3370.1930.026-1.021
03-1.9911.026-0.381-0.937
04-6.922-0.577-6.9221.234
051.386-6.922-6.922-6.922
061.386-6.922-6.922-6.922
07-6.922-6.922-6.9221.386
08-6.922-6.922-6.9221.386
091.037-6.9220.164-6.922
10-0.952-0.0080.931-2.458
11-1.0910.321-0.3810.472
12-0.3420.4360.08-0.417
130.270.186-0.622-0.053
140.408-0.322-1.020.344
150.617-0.887-1.9690.467
160.769-1.807-3.2020.493
170.652-2.925-2.5310.667
180.309-2.017-1.2430.796
190.158-1.33-0.1490.532
20-0.006-0.5370.1660.216
Standard thresholds
P-value Threshold
0.001 0.25991
0.0005 2.16461
0.0001 6.23026