Motif | GBX2.H12CORE.1.S.B |
Gene (human) | GBX2 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Gbx2 |
Gene synonyms (mouse) | Mmoxa, Stra7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | GBX2.H12CORE.1.S.B |
Gene (human) | GBX2 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Gbx2 |
Gene synonyms (mouse) | Mmoxa, Stra7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 20 |
Consensus | nvSTAATTASbvnhWWWWdn |
GC content | 31.23% |
Information content (bits; total / per base) | 15.455 / 0.773 |
Data sources | HT-SELEX |
Aligned words | 9258 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 10 experiments | median | 0.907 | 0.886 | 0.766 | 0.761 | 0.642 | 0.661 |
best | 0.997 | 0.996 | 0.981 | 0.977 | 0.96 | 0.938 | |
Methyl HT-SELEX, 2 experiments | median | 0.962 | 0.945 | 0.902 | 0.886 | 0.817 | 0.814 |
best | 0.983 | 0.971 | 0.973 | 0.957 | 0.949 | 0.929 | |
Non-Methyl HT-SELEX, 8 experiments | median | 0.79 | 0.767 | 0.656 | 0.657 | 0.579 | 0.594 |
best | 0.997 | 0.996 | 0.981 | 0.977 | 0.96 | 0.938 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.902 | 0.147 | 0.901 | 0.491 |
batch 2 | 0.809 | 0.726 | 0.786 | 0.532 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | GBX {3.1.1.11} (TFClass) |
TFClass ID | TFClass: 3.1.1.11.2 |
HGNC | HGNC:4186 |
MGI | MGI:95668 |
EntrezGene (human) | GeneID:2637 (SSTAR profile) |
EntrezGene (mouse) | GeneID:14472 (SSTAR profile) |
UniProt ID (human) | GBX2_HUMAN |
UniProt ID (mouse) | GBX2_MOUSE |
UniProt AC (human) | P52951 (TFClass) |
UniProt AC (mouse) | P48031 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 8 |
Methyl-HT-SELEX | 2 |
PCM | GBX2.H12CORE.1.S.B.pcm |
PWM | GBX2.H12CORE.1.S.B.pwm |
PFM | GBX2.H12CORE.1.S.B.pfm |
Alignment | GBX2.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | GBX2.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | GBX2.H12CORE.1.S.B_jaspar_format.txt |
MEME format | GBX2.H12CORE.1.S.B_meme_format.meme |
Transfac format | GBX2.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2393.5 | 3475.5 | 1818.5 | 1570.5 |
02 | 3244.5 | 2806.5 | 2374.5 | 832.5 |
03 | 314.0 | 6459.0 | 1580.0 | 905.0 |
04 | 0.0 | 1299.0 | 0.0 | 7959.0 |
05 | 9258.0 | 0.0 | 0.0 | 0.0 |
06 | 9258.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 9258.0 |
08 | 0.0 | 0.0 | 0.0 | 9258.0 |
09 | 6530.0 | 0.0 | 2728.0 | 0.0 |
10 | 892.0 | 2297.0 | 5873.0 | 196.0 |
11 | 776.0 | 3191.0 | 1580.0 | 3711.0 |
12 | 1643.0 | 3582.0 | 2508.0 | 1525.0 |
13 | 3033.0 | 2789.0 | 1241.0 | 2195.0 |
14 | 3483.0 | 1677.0 | 833.0 | 3265.0 |
15 | 4291.0 | 952.0 | 321.0 | 3694.0 |
16 | 4997.0 | 378.0 | 92.0 | 3791.0 |
17 | 4444.0 | 122.0 | 182.0 | 4510.0 |
18 | 3154.0 | 306.0 | 666.0 | 5132.0 |
19 | 2712.25 | 610.25 | 1993.25 | 3942.25 |
20 | 2301.75 | 1351.75 | 2732.75 | 2871.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.259 | 0.375 | 0.196 | 0.17 |
02 | 0.35 | 0.303 | 0.256 | 0.09 |
03 | 0.034 | 0.698 | 0.171 | 0.098 |
04 | 0.0 | 0.14 | 0.0 | 0.86 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.0 | 0.0 | 0.0 | 1.0 |
09 | 0.705 | 0.0 | 0.295 | 0.0 |
10 | 0.096 | 0.248 | 0.634 | 0.021 |
11 | 0.084 | 0.345 | 0.171 | 0.401 |
12 | 0.177 | 0.387 | 0.271 | 0.165 |
13 | 0.328 | 0.301 | 0.134 | 0.237 |
14 | 0.376 | 0.181 | 0.09 | 0.353 |
15 | 0.463 | 0.103 | 0.035 | 0.399 |
16 | 0.54 | 0.041 | 0.01 | 0.409 |
17 | 0.48 | 0.013 | 0.02 | 0.487 |
18 | 0.341 | 0.033 | 0.072 | 0.554 |
19 | 0.293 | 0.066 | 0.215 | 0.426 |
20 | 0.249 | 0.146 | 0.295 | 0.31 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.034 | 0.406 | -0.241 | -0.387 |
02 | 0.337 | 0.193 | 0.026 | -1.021 |
03 | -1.991 | 1.026 | -0.381 | -0.937 |
04 | -6.922 | -0.577 | -6.922 | 1.234 |
05 | 1.386 | -6.922 | -6.922 | -6.922 |
06 | 1.386 | -6.922 | -6.922 | -6.922 |
07 | -6.922 | -6.922 | -6.922 | 1.386 |
08 | -6.922 | -6.922 | -6.922 | 1.386 |
09 | 1.037 | -6.922 | 0.164 | -6.922 |
10 | -0.952 | -0.008 | 0.931 | -2.458 |
11 | -1.091 | 0.321 | -0.381 | 0.472 |
12 | -0.342 | 0.436 | 0.08 | -0.417 |
13 | 0.27 | 0.186 | -0.622 | -0.053 |
14 | 0.408 | -0.322 | -1.02 | 0.344 |
15 | 0.617 | -0.887 | -1.969 | 0.467 |
16 | 0.769 | -1.807 | -3.202 | 0.493 |
17 | 0.652 | -2.925 | -2.531 | 0.667 |
18 | 0.309 | -2.017 | -1.243 | 0.796 |
19 | 0.158 | -1.33 | -0.149 | 0.532 |
20 | -0.006 | -0.537 | 0.166 | 0.216 |
P-value | Threshold |
---|---|
0.001 | 0.25991 |
0.0005 | 2.16461 |
0.0001 | 6.23026 |