MotifGBX2.H12CORE.0.SM.B
Gene (human)GBX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gbx2
Gene synonyms (mouse)Mmoxa, Stra7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnvvbTAATTRvn
GC content37.45%
Information content (bits; total / per base)11.9 / 0.992
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8831

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.906 0.873 0.782 0.767 0.657 0.67
best 0.992 0.986 0.983 0.973 0.97 0.956
Methyl HT-SELEX, 2 experiments median 0.962 0.942 0.914 0.894 0.833 0.827
best 0.988 0.98 0.979 0.967 0.96 0.943
Non-Methyl HT-SELEX, 8 experiments median 0.802 0.77 0.671 0.665 0.587 0.599
best 0.992 0.986 0.983 0.973 0.97 0.956

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.956 0.545 0.924 0.525
batch 2 0.865 0.814 0.863 0.609
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyGBX {3.1.1.11} (TFClass)
TFClass IDTFClass: 3.1.1.11.2
HGNCHGNC:4186
MGIMGI:95668
EntrezGene (human)GeneID:2637
(SSTAR profile)
EntrezGene (mouse)GeneID:14472
(SSTAR profile)
UniProt ID (human)GBX2_HUMAN
UniProt ID (mouse)GBX2_MOUSE
UniProt AC (human)P52951
(TFClass)
UniProt AC (mouse)P48031
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 8
Methyl-HT-SELEX 2
PCM
ACGT
012236.252058.252433.252103.25
021620.03692.02149.01370.0
031985.02376.04120.0350.0
04341.04695.01397.02398.0
050.00.00.08831.0
068831.00.00.00.0
078831.00.00.00.0
080.00.00.08831.0
091.056.089.08685.0
103908.00.04864.059.0
111069.753470.753307.75982.75
121389.02504.02475.02463.0
PFM
ACGT
010.2530.2330.2760.238
020.1830.4180.2430.155
030.2250.2690.4670.04
040.0390.5320.1580.272
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0060.010.983
100.4430.00.5510.007
110.1210.3930.3750.111
120.1570.2840.280.279
PWM
ACGT
010.013-0.070.097-0.048
02-0.3090.514-0.027-0.477
03-0.1060.0730.623-1.836
04-1.8620.754-0.4570.083
05-6.88-6.88-6.881.386
061.386-6.88-6.88-6.88
071.386-6.88-6.88-6.88
08-6.88-6.88-6.881.386
09-6.516-3.636-3.1871.369
100.571-6.880.789-3.585
11-0.7230.4520.404-0.808
12-0.4630.1260.1140.109
Standard thresholds
P-value Threshold
0.001 2.401275
0.0005 4.41542
0.0001 8.00025