MotifGATA6.H12INVIVO.0.PSM.A
Gene (human)GATA6
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusnnnvWGATAASv
GC content39.9%
Information content (bits; total / per base)11.486 / 0.957
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1007

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 29 (190) 0.933 0.973 0.86 0.933 0.917 0.964 3.326 4.063 186.939 450.854
Mouse 7 (47) 0.925 0.949 0.845 0.877 0.903 0.92 3.185 3.351 233.854 462.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.974 0.952 0.967 0.943 0.944 0.918
best 0.978 0.959 0.975 0.955 0.96 0.938
Methyl HT-SELEX, 1 experiments median 0.978 0.959 0.975 0.955 0.96 0.938
best 0.978 0.959 0.975 0.955 0.96 0.938
Non-Methyl HT-SELEX, 1 experiments median 0.969 0.944 0.958 0.931 0.928 0.897
best 0.969 0.944 0.958 0.931 0.928 0.897

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 7.66 3.398 0.49 0.273

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.696 0.365 0.725 0.508
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.6
HGNCHGNC:4174
MGIMGI:107516
EntrezGene (human)GeneID:2627
(SSTAR profile)
EntrezGene (mouse)GeneID:14465
(SSTAR profile)
UniProt ID (human)GATA6_HUMAN
UniProt ID (mouse)GATA6_MOUSE
UniProt AC (human)Q92908
(TFClass)
UniProt AC (mouse)Q61169
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 29 human, 7 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01254.0260.0293.0200.0
02245.0290.0239.0233.0
03317.0174.0280.0236.0
04180.0399.0310.0118.0
05653.024.01.0329.0
061.00.01003.03.0
07999.03.04.01.0
082.03.06.0996.0
09953.05.06.043.0
10951.05.041.010.0
1168.0146.0779.014.0
12426.0184.0367.030.0
PFM
ACGT
010.2520.2580.2910.199
020.2430.2880.2370.231
030.3150.1730.2780.234
040.1790.3960.3080.117
050.6480.0240.0010.327
060.0010.00.9960.003
070.9920.0030.0040.001
080.0020.0030.0060.989
090.9460.0050.0060.043
100.9440.0050.0410.01
110.0680.1450.7740.014
120.4230.1830.3640.03
PWM
ACGT
010.0090.0320.151-0.228
02-0.0270.141-0.052-0.077
030.229-0.3660.106-0.064
04-0.3330.4580.207-0.75
050.949-2.288-4.5310.266
06-4.531-4.9881.377-3.982
071.373-3.982-3.79-4.531
08-4.219-3.982-3.491.37
091.326-3.629-3.49-1.735
101.324-3.629-1.78-3.073
11-1.291-0.541.125-2.78
120.523-0.3110.375-2.078
Standard thresholds
P-value Threshold
0.001 4.06347
0.0005 5.155645
0.0001 7.592655