MotifGATA4.H12INVITRO.0.PSM.A
Gene (human)GATA4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata4
Gene synonyms (mouse)Gata-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensusvWGATAASv
GC content38.44%
Information content (bits; total / per base)9.958 / 1.106
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 25 (162) 0.907 0.958 0.822 0.909 0.89 0.939 2.968 3.503 162.409 414.244
Mouse 40 (192) 0.888 0.949 0.786 0.898 0.85 0.929 2.658 3.422 160.102 348.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.985 0.971 0.977 0.964 0.935 0.922
best 0.987 0.977 0.984 0.969 0.974 0.958
Methyl HT-SELEX, 1 experiments median 0.985 0.973 0.982 0.969 0.972 0.956
best 0.985 0.973 0.982 0.969 0.972 0.956
Non-Methyl HT-SELEX, 3 experiments median 0.985 0.968 0.972 0.959 0.897 0.887
best 0.987 0.977 0.984 0.968 0.974 0.958
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.4
HGNCHGNC:4173
MGIMGI:95664
EntrezGene (human)GeneID:2626
(SSTAR profile)
EntrezGene (mouse)GeneID:14463
(SSTAR profile)
UniProt ID (human)GATA4_HUMAN
UniProt ID (mouse)GATA4_MOUSE
UniProt AC (human)P43694
(TFClass)
UniProt AC (mouse)Q08369
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 25 human, 40 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01152.0433.0313.0102.0
02638.039.016.0307.0
034.03.0993.00.0
04992.03.02.03.0
0510.04.012.0974.0
06909.03.09.079.0
07797.014.0171.018.0
08111.0265.0587.037.0
09349.0250.0343.058.0
PFM
ACGT
010.1520.4330.3130.102
020.6380.0390.0160.307
030.0040.0030.9930.0
040.9920.0030.0020.003
050.010.0040.0120.974
060.9090.0030.0090.079
070.7970.0140.1710.018
080.1110.2650.5870.037
090.3490.250.3430.058
PWM
ACGT
01-0.4930.5460.223-0.887
020.933-1.821-2.6530.204
03-3.783-3.9751.374-4.982
041.373-3.975-4.213-3.975
05-3.066-3.783-2.9091.355
061.286-3.975-3.156-1.137
071.155-2.773-0.377-2.546
08-0.8030.0580.85-1.872
090.3320.00.314-1.439
Standard thresholds
P-value Threshold
0.001 4.755895
0.0005 5.799565
0.0001 7.608425