MotifGATA3.H12INVIVO.1.SM.B
Gene (human)GATA3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata3
Gene synonyms (mouse)Gata-3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnvAGATAAGRW
GC content30.75%
Information content (bits; total / per base)14.816 / 1.347
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words436

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 54 (340) 0.662 0.835 0.554 0.773 0.716 0.89 1.969 3.18 87.953 250.745
Mouse 29 (173) 0.687 0.759 0.594 0.683 0.711 0.766 2.064 2.363 121.886 309.538

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.849 0.82 0.7 0.696 0.593 0.615
best 0.992 0.987 0.988 0.98 0.983 0.973
Methyl HT-SELEX, 1 experiments median 0.992 0.987 0.988 0.98 0.983 0.973
best 0.992 0.987 0.988 0.98 0.983 0.973
Non-Methyl HT-SELEX, 5 experiments median 0.848 0.815 0.691 0.694 0.585 0.611
best 0.987 0.978 0.983 0.971 0.975 0.96

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.259 6.056 0.173 0.109

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.899 0.24 0.895 0.496
batch 2 0.638 0.269 0.622 0.448
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.3
HGNCHGNC:4172
MGIMGI:95663
EntrezGene (human)GeneID:2625
(SSTAR profile)
EntrezGene (mouse)GeneID:14462
(SSTAR profile)
UniProt ID (human)GATA3_HUMAN
UniProt ID (mouse)GATA3_MOUSE
UniProt AC (human)P23771
(TFClass)
UniProt AC (mouse)P23772
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 54 human, 29 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
01110.572.583.5169.5
02148.0191.064.033.0
03372.00.00.064.0
040.00.0436.00.0
05436.00.00.00.0
060.00.00.0436.0
07436.00.00.00.0
08436.00.00.00.0
090.031.0405.00.0
10321.051.056.08.0
1150.039.046.0301.0
PFM
ACGT
010.2530.1660.1920.389
020.3390.4380.1470.076
030.8530.00.00.147
040.00.01.00.0
051.00.00.00.0
060.00.00.01.0
071.00.00.00.0
081.00.00.00.0
090.00.0710.9290.0
100.7360.1170.1280.018
110.1150.0890.1060.69
PWM
ACGT
010.013-0.401-0.2620.437
020.3020.555-0.523-1.164
031.218-4.287-4.287-0.523
04-4.287-4.2871.376-4.287
051.376-4.287-4.287-4.287
06-4.287-4.287-4.2871.376
071.376-4.287-4.287-4.287
081.376-4.287-4.287-4.287
09-4.287-1.2231.302-4.287
101.071-0.744-0.653-2.452
11-0.763-1.003-0.8441.007
Standard thresholds
P-value Threshold
0.001 2.50816
0.0005 3.873205
0.0001 6.548225