MotifGATA3.H12INVITRO.0.PS.A
Gene (human)GATA3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata3
Gene synonyms (mouse)Gata-3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensusnhGATAAvn
GC content35.59%
Information content (bits; total / per base)9.409 / 1.045
Data sourcesChIP-Seq + HT-SELEX
Aligned words9193

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 54 (340) 0.791 0.928 0.639 0.871 0.764 0.909 2.113 3.178 135.403 376.444
Mouse 29 (173) 0.802 0.859 0.662 0.745 0.763 0.828 2.198 2.58 201.086 467.046

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.921 0.885 0.776 0.764 0.631 0.657
best 0.988 0.98 0.987 0.977 0.985 0.973
Methyl HT-SELEX, 1 experiments median 0.988 0.98 0.987 0.977 0.985 0.973
best 0.988 0.98 0.987 0.977 0.985 0.973
Non-Methyl HT-SELEX, 5 experiments median 0.918 0.879 0.761 0.757 0.618 0.649
best 0.987 0.978 0.984 0.973 0.978 0.964

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.745 7.037 0.174 0.106

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.945 0.546 0.892 0.516
batch 2 0.688 0.351 0.701 0.522
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.3
HGNCHGNC:4172
MGIMGI:95663
EntrezGene (human)GeneID:2625
(SSTAR profile)
EntrezGene (mouse)GeneID:14462
(SSTAR profile)
UniProt ID (human)GATA3_HUMAN
UniProt ID (mouse)GATA3_MOUSE
UniProt AC (human)P23771
(TFClass)
UniProt AC (mouse)P23772
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 54 human, 29 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
012459.02788.02197.01749.0
024801.251410.25550.252431.25
031.024.09159.09.0
049192.00.01.00.0
050.00.00.09193.0
068920.0159.02.0112.0
077473.01002.0399.0319.0
081352.52673.54113.51053.5
092956.52132.52831.51272.5
PFM
ACGT
010.2670.3030.2390.19
020.5220.1530.060.264
030.00.0030.9960.001
041.00.00.00.0
050.00.00.01.0
060.970.0170.00.012
070.8130.1090.0430.035
080.1470.2910.4470.115
090.3220.2320.3080.138
PWM
ACGT
010.0680.193-0.045-0.273
020.736-0.488-1.4260.056
03-6.553-4.4721.382-5.318
041.385-6.916-6.553-6.916
05-6.916-6.916-6.9161.386
061.355-2.658-6.287-3.002
071.178-0.829-1.746-1.969
08-0.5290.1510.582-0.779
090.252-0.0750.208-0.59
Standard thresholds
P-value Threshold
0.001 5.186725
0.0005 6.238055
0.0001 7.52316