MotifGATA2.H12INVITRO.1.P.B
Gene (human)GATA2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusnbbnnnnndvWGATAASv
GC content47.86%
Information content (bits; total / per base)10.281 / 0.571
Data sourcesChIP-Seq
Aligned words999

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 41 (254) 0.842 0.953 0.717 0.907 0.821 0.938 2.545 4.111 168.272 322.26
Mouse 23 (136) 0.808 0.958 0.697 0.906 0.797 0.954 2.6 4.217 141.745 330.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.917 0.867 0.887 0.834 0.836 0.788
best 0.926 0.878 0.901 0.851 0.86 0.81
Methyl HT-SELEX, 1 experiments median 0.926 0.878 0.901 0.851 0.86 0.81
best 0.926 0.878 0.901 0.851 0.86 0.81
Non-Methyl HT-SELEX, 1 experiments median 0.908 0.856 0.872 0.818 0.813 0.766
best 0.908 0.856 0.872 0.818 0.813 0.766

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.741 5.51 0.233 0.107

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.654 0.281 0.609 0.423
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.2
HGNCHGNC:4171
MGIMGI:95662
EntrezGene (human)GeneID:2624
(SSTAR profile)
EntrezGene (mouse)GeneID:14461
(SSTAR profile)
UniProt ID (human)GATA2_HUMAN
UniProt ID (mouse)GATA2_MOUSE
UniProt AC (human)P23769
(TFClass)
UniProt AC (mouse)O09100
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 41 human, 23 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01187.0238.0214.0360.0
02119.0141.0444.0295.0
03158.0249.0433.0159.0
04238.0202.0331.0228.0
05232.0237.0346.0184.0
06243.0236.0332.0188.0
07207.0246.0370.0176.0
08242.0256.0305.0196.0
09274.0158.0390.0177.0
10153.0380.0399.067.0
11683.040.018.0258.0
125.02.0992.00.0
13990.02.05.02.0
1423.021.010.0945.0
15868.018.027.086.0
16801.020.0129.049.0
17143.0177.0615.064.0
18331.0190.0434.044.0
PFM
ACGT
010.1870.2380.2140.36
020.1190.1410.4440.295
030.1580.2490.4330.159
040.2380.2020.3310.228
050.2320.2370.3460.184
060.2430.2360.3320.188
070.2070.2460.370.176
080.2420.2560.3050.196
090.2740.1580.390.177
100.1530.380.3990.067
110.6840.040.0180.258
120.0050.0020.9930.0
130.9910.0020.0050.002
140.0230.0210.010.946
150.8690.0180.0270.086
160.8020.020.1290.049
170.1430.1770.6160.064
180.3310.190.4340.044
PWM
ACGT
01-0.287-0.048-0.1530.364
02-0.734-0.5660.5720.165
03-0.454-0.0030.547-0.448
04-0.048-0.2110.28-0.09
05-0.073-0.0520.324-0.303
06-0.027-0.0560.283-0.282
07-0.186-0.0150.391-0.347
08-0.0310.0250.199-0.24
090.092-0.4540.443-0.341
10-0.4860.4170.466-1.297
111.002-1.796-2.5450.032
12-3.621-4.2121.374-4.981
131.372-4.212-3.621-4.212
14-2.319-2.404-3.0651.326
151.241-2.545-2.17-1.053
161.161-2.449-0.654-1.601
17-0.553-0.3410.897-1.342
180.28-0.2710.55-1.705
Standard thresholds
P-value Threshold
0.001 4.71486
0.0005 5.61636
0.0001 7.39246